There is little information regarding flow cytometric DNA analyses of benign breast lesions. This prospective study consists of mammographic and pathological correlation of DNA flow cytometric analyses of specimen mammography-guided fine-needle aspirates (FNAs) of 189 consecutive benign breast lesions and 114 FNAs of adjacent normal tissue as a control. Clinical follow-up was also performed. An...

Objective: The aim of this study was to determine whether the suggested threshold ADC measurements can be used to characterize benign and malignant breast lesions. Materials and Methods: Sixty two female patients between the ages of 15-64 years (mean age, 44 years) with 49 benign and 25 malignant histopathologically verified breast masses were included in this study. The patients were examined ...

background: oral lichen planus (olp) is a relatively common chronic inflammatory muco-cutaneous disease classified among the potentially malignant lesions of oral mucosa. in this study we evaluated tissue expression of p 53 ، ki-67 in olp com­pared to normal oral mucosa. methods: specimens (formalin-fixed and paraffin- embedded) of 44 lesions of olp and 30 controls referred to immuno­histochem­...

S. B. Thakur, L. Bartella, N. M. Ishill, E. A. Morris, L. Liberman, D. D. Dershaw, H. Hricak, J. A. Koutcher, W. Huang Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, Epidemiology-Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, United States Introduction In ...

Cervical cancer is always preceded by epithelial lesions which have larger and more densely spaced nuclei than normal tissue. Detecting and removing these lesions prevents the development of cervical cancer. A proposed method to detect precancerous lesion in vivo is to use the nuclear size and density information from fiber optic confocal images of the cervical epithelial tissue to classify the...

I. Cultures of B. coli communis, B. typhosus and Staph. pyogenes aureus, when injected into the tissue of the normal spleen, soon disappear from that organ, and indeed from the normal body generally. II. Bacteria injected into a spleen after the whole or a part of the vessels have been tied, multiply in the spleen with great rapidity and continue to supply bacteria to the blood, whence in the h...

background and aims. many oral squamous cell carcinomas develop from potentially malignant disorders (pmds) which include a variety of lesions and conditions characterized by an increased risk for malignant transformation. this study evaluated the quantitative expression of egfr in normal oral mucosa, oral leukoplakia and oral submucous fibrosis to predict the malignant risk in compliance with ...

Background Endometriosis is a common gynecological disease, can cause severe pelvic pain. Studies demonstrated the presence of sensory nerve fibers in endometrium of endometriosis patient. Nevertheless, no information is available on mechanisms of sensory nerve formation in eutopic or ectopic lesions. Since HOX genes have important roles in both reproductive tract and nerve growth, we decided t...

Lesions of the brain’s white matter are common findings in MR examinations of elderly subjects. A fully automatic method for segmenting white matter lesions is proposed here. The joint probability of multimodality MR image intensities is used as a feature to segment lesions, because lesion intensities usually are outliers of the normal tissue intensities and the lesions’ joint intensity probabi...

Myocardial infarction is commonly considered as a leading cause of cardiovascular disease taking the lives of seven million people annually. Liver dysfunction is associated with cardiac diseases. The profile of abnormal liver functions in heart failure is not clearly defined. This study was designed to investigate the protective effects of betaine on liver injury after myocardial infarction ind...