Gholam Hossein Farjah
Neurophysiology Research Center, Department of Anatomy, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran
[ 1 ] - Oral administration of alanyl-glutamine and glutamine improve random pattern dorsal skin flap survival in rats
Objective(s): Skin flap necrosis is the most common postoperative side effect in reconstructive surgeries. Glutamine (GLN) has been shown to accelerate wound healing process. The purpose of this study was to evaluate the effects of GLN either in free form or in the dipeptide form along with L- alanyl (Ala-GLN) on random skin flaps survival in rats.Materials and Methods: Dorsal skin flaps with c...
[ 2 ] - The effect of bone marrow mesenchymal stem cells on recovery of skeletal muscle after neurotization surgery in rat
Objective(s): When the nerve is injured near its entrance to the muscle belly, we cannot perform conventional methods. One useful method in such a situation is neurotization surgery. In this study, Bone marrow mesenchymal stem cells (BMSCs) implanted into the paralyzed muscle after neurotization surgery. These cells can stimulate axon growth and motor endplate formation, also prevent muscle atr...
[ 3 ] - Using Eggshell Membrane as Nerve Guide Channels in Peripheral Nerve Regeneration
Objective(s): The aim of this study was to evaluate the final outcome of nerve regeneration across the eggsell membrane (ESM) tube conduit in comparison with autograft. Materials and Methods: Thirty adult male rats (250-300 g) were randomized into (1) ESM conduit, (2) autograft, and (3) sham surgery groups. The eggs submerged in 5% acetic acid. The decalcifying membranes were cut into four pie...
[ 4 ] - The effect of chick embryo amniotic fluid on sciatic nerve regeneration of rats
The purpose of this experimental study was to evaluate the effect of chicken amniotic fluid (AF) on a cross section of rat sciatic nerves. Thirty adult male Sprague-Dawley rats weighing 275 to 300 g, were randomized into three groups treated with (1) amniotic fluid or AF (n=10), (2) normal saline or NS (n=10), and (3) sham surgery (n=10). The AF was aspirated from the amniotic cavity of incubat...
[ 5 ] - The effect of short-term treatments of a gonadotropinreleasing hormone analog (buserelin) on sciatic nerve regeneration
Gonadotropin-releasing hormone (GnRH) has neuromodulatory roles in central and peripheral nervous systems. The purpose of this study is to evaluate the effect of GnRH analog (buserelin) on peripheral nerve regeneration. Forty adult male rats were divided into buserelin-treated, normal saline, sham surgery, and castrated + buserelin groups. The left sciatic nerve was crushed by a fine forceps an...
[ 6 ] - Hepatoprotective effects of betaine on liver damages followed by myocardial infarction
Myocardial infarction is commonly considered as a leading cause of cardiovascular disease taking the lives of seven million people annually. Liver dysfunction is associated with cardiac diseases. The profile of abnormal liver functions in heart failure is not clearly defined. This study was designed to investigate the protective effects of betaine on liver injury after myocardial infarction ind...
[ 7 ] - Protective effect of aqueous spinach (Spinacia oleracea L.) extract on spinal cord ischemia-reperfusion injury in rats
Operation on the thoraco-abdominal aorta may lead to paraplegia or paraparesis is after spinal ischemia/reperfusion (I/R) injury. In this study, we investigated the protective effect of the spinach extract on spinal cord I/R injury. Thirty-five male Sprague-Dawley rats were divided into five groups: Intact, sham surgery, normal saline (NS), low dose spinach extract (20 mg kg-1), high...
[ 8 ] - بررسی فراساختاری اثر توام ژل کلاژن و مجرای پلی وینیلیدین فلوراید بر روی رژنراسیون عصب محیطی موش صحرایی
مقدمه: تشکیل میلین به بلوغ و تکامل سیتو اسکلتال آکسون و میتو کندری وابسته است . ژل کلاژن بصورت اختصاصی در تنظیم و تکامل سیتواسکلتان آکسون نقش دارد.روش کار: این تحقیق یک مطالعه تجربی است که از 48 سر موش صحرایی نر (gr250- 200) استفاده شد. پس از قطع عصب سیاتیک، 1 سانتی متر از عصب برداشته شد و شکاف حاصله توسط یکی از 4 روش زیر ترمیم شد ( مجرای پلی وینیلیدین فلوراید یا PVDF (Ploy Vinyli Dene Fluoride...
[ 9 ] - بررسی اثر تجویز توام یوبی کینون و ویتامین C بر تغییرات رفتاری و هیستولوژیکی و پارامترهای بیوشیمیایی در مدل contusion ضایعه نخاعی دررت
Background and purpose: Spinal cord injury (SCI) is one of the most disabling diseases with various physical and psychological consequences. One of the treatments of SCI is using agents that have neuroprotective effects such as Vitamin C and ubiquinone. This research aimed at investigating the effect of co-administration of these agents on rat experimental model of SCI. Materials and methods: ...
[ 10 ] - استفاده از کانال راهنمای عصب در ترمیم عصب محیطی
Although the nerve auto graft still remains the clinical Gold standard in repairing nerve injury gaps, many advances have been achieved to guide regenerating axons across the lesion. Functional recovery after peripheral nerve lesion is depended upon accurate regeneration of axons to their original target tissues. To increase the prospects of axonal regeneration and functional recovery, research...
[ 11 ] - تاثیر آموزش اصطلاحات پزشکی بر یادگیری درس آناتومی دانشجویان پیراپزشکی دانشگاه علوم پزشکی ارومیه
سابقه و هدف: هدف از این مطالعه مقایسه سخنرانی وآموزش مفاهیم واژگان و اصطلاحات بر یادگیری درس آناتومی دانشجویان رادیولوژی است. مواد و روشها: تعداد 50 نفر دانشجوی ترم اول رادیولوژی به بصورت تصادفی در دو گروه کنترل و آزمایشی تقسیم شدند. برای گروه کنترل مباحث آناتومی به روش سخنرانی و برای گروه آزمایش در هنگام تدریس با مفاهیم و اصطلاحات آناتومی آاشنا شدند. از دانشجویان آزمون های میان ترم و پایان تر...
[ 12 ] - استفاده از ورید نافی انسانی بعنوان کانال راهنمای عصب در رژنراسیون عصب سیاتیک موش صحرایی
زمینه و هدف: آسیب اعصاب محیطی شایع است. اگر چه اتوگرافت عصب هنوز هم بعنوان روش استاندارد طلایی برای ترمیم شکاف ناشی از آسیب های اعصاب محیطی می باشد، اما زیان هایی دارد. از ورید نافی انسان برای باز سازی عروق استفاده می شود. هدف از انجام این مطالعه مقایسه ارزیابی نتایج ترمیم عصب از طریق ورید نافی با اتوگرافت است. مواد و روش کار: در این مطالعه از 30 سر موش صحرایی نر استفاده شد. موش ها به سه گروه ش...
[ 13 ] - Protective effect of lutein on spinal cord ischemia-reperfusion injury in rats
Objective(s): Paraplegia is deterioration in motor or sensory function of the lower limbs that can occur after modification of a thoracoabdominal aortic aneurysm. The purpose of this survey was to determine the protective action of lutein on spinal cord ischemia-reperfusion (I-R) damage. Materials and Methods: Thirty-five male rats were distributed into five groups: intact, sham, dimethyl sulfo...
[ 14 ] - The effect of lycopene in egg shell membrane guidance channel on sciatic nerve regeneration in rats
Objective(s): Peripheral nerves are commonly damaged. Although the nerve autograft still subsists the gold standard in surgery of nerve injury gaps, it has severe detriment. The egg shell membrane (ESM) is a natural material, which has a great potential in practice. The aim of this survey was to appraise the effect of lycopene and the ESM nerve guidance channel on scia...
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