Over the last two decades, deep brain stimulation has become widely accepted as a treatment for Parkinson’s disease, dystonia and tremor, and its use is increasing in disorders such as obsessivecompulsive disorder, depression and pain. The primary objective is always to achieve symptom suppression with few or no side effects; in other words, to attain as wide a therapeutic window as possible. I...

223 Useful animal models for the investigation of autoimmune disorders that involve the brain are essential, especially in children in whom access to the CNS is limited. The paucity of such models can hinder an understanding of causation, pathogenic mechanisms, and treatments. This is particularly true when one is investigating postulated antibody-mediated disorders in which evidence supporting...

Introduction The localization of cognitive domains can be achieved by functional imaging modalities such as fMRI, PET and MEG. It was recently shown that voxel-wise correlation between high resolution quantitative structural MRI (e.g. diffusion tensor imaging indices, DTI) and various behavioral measures allows brain localization of cognitive performance. This approach hypothesizes that inter-s...

Background & Aims: Ulcerative colitis is one of the inflammatory bowel diseases with unknown etiology. Genetic and environmental factors are thought to be effective in this disease. According to the limited studies in our country, general assessment of demographic features and clinical symptoms seems to be essential. Methods: In this prospective and cross-sectional study, 85 cases of ulcerat...

Abstract:Purpose:This study was designed determine the efficacy of bupropion versus placebo in subjects with negative symptoms of schizophrenia.Methods:A convenience sample of 40 patients of both genders aged 18-60 years who were living in psychiatric care centers were randomly treated with bupropion (started with 75 mg twice a day; increased to 100 mg thrice daily) or placebo. The diagnosis of...

Fungal spores are continuously deposited on the leaf surfaces by wind impaction, sedimentation and rain wash-out from the atmosphere and splash-dispersal. They reside and act as asymptomatic mutualists, benign commensals or latent pathogens. A slight imbalance in this relation can lead to pathogenic phase of the fungi, resulting in a variety of symptoms on leaves viz. discoloration, blight, soo...

Treatment-emergent mania has been reported with various selective serotonin reuptake inhibitors (SSRIs) (Diler and Avci, 1999; Grubbs, 1997). We report four cases of citalopram-induced mania in children. Case 1. A 6-year-old boy with a family history of obsessivecompulsive disorder (OCD) was diagnosed with severe depression without psychotic symptoms. He developed mania without psychotic sympto...

garbage collectors are occupationally exposed to a variety of airborne contaminants. the main objective of this study was to evaluate the respiratory health of garbage collectors. this study was carried out in fars province, south of iran. a group of 105 garbage collectors and 93 referent subjects were investigated. a standard questionnaire was administered to both groups. furthermore, subjects...

conclusions mild traumatic brain injuries despite of the normal ct scan and history of substance abuse are closely related to psychological symptoms. therefore, it is recommended that patients with brain trauma 6 months post-injury and subjects with a history of substance abuse be evaluated for psychological distress to support better rehabilitation. background it is well-known that severe brai...

recent epidemiological studies show that obsessive-compulsive disorder (ocd) and its comorbidity with psychiatric problems is more prevalent among children and adolescents than was previously believed. the primary aim of the current study is to investigate the point-prevalence rate of obsessive compulsive symptoms in a sample of adolescent high school student in iran. a two-stage epidemiologica...