نتایج جستجو برای: ocular drug delivery
تعداد نتایج: 799878 فیلتر نتایج به سال:
Background and purpose: In ocular delivery the physiological constraints imposed by the protective mechanisms of the eye lead to low absorption of drugs, resulting in a short duration of the therapeutic effect. Thus using in-situ gelling systems could increase the residence time of the drug in the eye. These systems are instilled as drops into the eye and undergo a sol-to-gel transition in the ...
Objectives: Owing to the increasing number of patients suffering from posterior eye disorders, efficient medicine delivery segment is now in great demand clinical services. With unmet medical requirements, an important therapeutic target. So, physicians should be informed new indications and current strategies drug when technologies enter market.
 Summary: The most common causes vision imp...
To target chronic inflammatory ocular surface diseases, a drug delivery platform is needed that is safe, possesses immunomodulatory properties, and can be used either for drug delivery, or as a foreign antigen carrier. A new therapeutic approach that we have previously proposed uses nonliving bacterial ghosts (BGs) as a carrier-delivery system which can be engineered to carry foreign antigens a...
The most sensitive and complex organ in the human body is eye, so special attention should be needed for administration of pharmaceutical substances into eye. It one difficult researchers preparation drug delivery to anatomical characteristics physiological properties eye considered delivery. dosage forms depend upon anatomy physiology Drug on outer part as well inner ocular structure therapy a...
IMPORTANCE OF THE FIELD The use of topical agents poses unique and challenging hurdles for drug delivery. Topical steroids effectively control ocular inflammation, but are associated with the well-recognized dilemma of patient compliance. Although administration of topical antimicrobials as prophylaxis is acceptable among ophthalmologists, this common practice has no sound evidence base. Develo...
objective(s): ketotifen fumarate (kf) is a selective and noncompetitive histamine antagonist (h1-receptor) that is used topically in the treatment of allergic conditions of rhinitis and conjunctivitis. the aim of this study was to formulate and improve an ophthalmic delivery system of kf.ocular nanoparticles were prepared with the objective of reducing the frequency of administration and obtain...
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