background: intracranial lesions of the pituitary gland are common pituitary adenomas, accounting for 6-10% of all symptomatic intracranial tumors. in this retrospective study, the clinicopathologic features and survival rate of pituitary adenomas were evaluated. methods: the present retrospective study was conducted on 83 patients with pituitary adenomas, referring to radiation oncology depart...

ACKNOWLEDGMENTS I would like to thank everyone who supported and helped me through the progress and completion of this dissertation. I would like to express my appreciation and special thanks to my advisor, Dr. Aria Nosratinia, for his continuous advice, guidance and support throughout my graduate studies at UTD. serving on my supervisory committee, for giving their precious time to read my dis...

The miniature craft cruises silently through a blood vessel. Sneaking through a hole in the vessel wall, it infiltrates a tumor and uses an on-board antibody key to gain entry into a cancer cell. Once inside, the sleek ship deploys its anticancer cargo to destroy the tumor. Mission accomplished. This vision of nanomedicine, commonly portrayed in animations from the early 2000s, promised that na...

Aim—Two unexplored aspects for irinotecan and cisplatin (I&C) combination chemotherapy are (1) actively targeting both drugs to a specific diseased cell type and (2) delivering both drugs on the same vehicle to ensure their synchronized entry into the cell at a well-defined ratio. In this work we report the use of targeted polymeric nanoparticles (NPs) to co-encapsulate and deliver I&C to cance...

Researchers often use clinical trials to collect the data needed to evaluate some hypothesis, or produce a classifier. During this process, they have to pay the cost of performing each test. Many studies will run a comprehensive battery of tests on each subject, for as many subjects as their budget will allow – i.e., “round robin” (RR). We consider a more general model, where the researcher can...

Objectives: The present study has been conducted to determine the effectiveness of cognitivebehavioral group-therapy on the development of visually impaired adolescents’ self-concept. Methods: This study is a semi-experimental pre-test and post-test model. The study population consisted of visually impaired male students of the primary and secondary high school at the Omid...

The endometrium is the mucous lining the uterine cavity comprised of a basal and a functional layer being the latter the one that sheds during menses and regenerates from the basal portion. The main cell populations within the functional stratus are epithelial and stromal cells accompanied by a variable number of leukocytes. Epithelial cells are found covering the luminal surface and tubular gl...

this research was conducted to investigate genotyp×environment interaction for grain yield of ten wheat cultivars in 8 environments (combinations of two nitrogen fertilizer treatment and four irrigation regimes). analysis of additive main effects (analysis of variance) and multiplicative interaction effects (principal component analysis) revealed that the effects of genotype, environment and ge...

introduction: esophageal squamous-cell carcinoma (scc) is one of the most common malignancies in iran. to reduce the incidence of esophageal scc, it is important to recognize the controllable risk factors and prevent them. celiac disease is widely known as a possible risk factor for esophageal scc.  thus, we decided to assess the frequency of celiac disease in esophageal scc patients in north e...