The malignant potential of oral lichen planus (OLP) has been a matter of serious controversy. We aimed to detect chromosomal numerical aberrations in cells of brush samples collected from affected mucosa. The samples were simultaneously analyzed for morphology and fluorescent in situ hybridization (FISH) with chromosomes 2 and 8 centromeric probes. We analyzed 57 persons with OLP and 33 control...

Background: Oral lichen planus (OLP) is a chronic inflammatory autoimmune oral mucosa disease. The ulcerative type of OLP presents as erythematous ulceration with mucosal erosions surrounding whitish striae. aetiology unknown, but can be predisposed by psychological factors. Purpose: Reporting stress. Case: A 36 years old woman complained very painful ulcer in the right buccal and grey-purple l...

Background: The association between oral Lichen planus (OLP) as a common oral disease and HCV infection as an etiological factor in the development of hepatocellular carcinoma has been widely reported. However, there are wide geographical variations in the reported prevalence. This study was performed to determine the prevalence of L. planus in HCV+ patients in Shiraz, southern Iran. Methods: S...

lichen planus is a chronic inflammatory mucocutaneous disease. mucosal lesions are classified into six clinical forms and there is malignant potential for two forms of olp; therefore, follow-up should be considered. there are many un-established etiological factors for olp and some different treatment modalities are based on etiology. the aims of current olp therapy are to eliminate mucosal ery...

Steroids have been found to be effective in treating symptomatic oral lichen planus (OLP) by reducing pain and inflammation. In fact, systemic corticosteroids should be reserved for acute exacerbation, and multiple or widespread lesions. They may be indicated in patients whose condition is unresponsive to topical steroids. However, various potent topical steroids have been reported to be effect...

Introduction: Lichen planus is a chronic inflammatory disease in oral mucosa and skin. Recently, reports have demonstrated a possible relationship between lichen planus and liver diseases. During the past decade, there has been a hypothesis regarding viral etiological agents that have been found to be in association with hepatotrophic viruses known as Hepatitis B and C with LP. This research wa...

OBJECTIVES Lichen planus (LP) is a chronic inflammatory mucocutaneous disease. Its treatment is often symptomatic and includes topical and systemic corticosteroids. Although corticosteroid therapy is usually successful, it has side effects and thus, an alternative treatment is favorable. The aim of this study was to compare the efficacy of topical curcumin and triamcinolone for treatment of ora...

BACKGROUND AND AIMS Lichen planus is a chronic inflammatory disorder with unspecified etiology, appearing as a result of stress, genetic predisposition and immunologic factors. Erosive type of the disease is more important because of its clinical symptoms of pain, irritation and malignancy risk. Despite various medications used, a definite cure for lichen planus is un-known. Regarding the effec...

BACKGROUND Oral lichen planus (OLP) is a chronic inflammatory disease that causes bilateral white striations, papules, or plaques on the buccal mucosa, tongue, and gingivae. Erythema, erosions, and blisters may or may not be present. Several empirical therapies have been used in the treatment of (OLP). OBJECTIVE To evaluate the effect of low level laser therapy (LLLT) versus topical steroids ...