Recurrent Aphthous Stomatitis (RAS) is a disorder characterized by recurring ulcers in the oral mucosa in patients with no other signs of disease. This condition is also called as Sutton’s disease, especially in the case of major, multiple or recurring ulcers. RAS appears to represent several pathological states with similar clinical manifestations, including immunologic disorders, hematologic ...

IL: interleukin RAS: recurrent aphthous stomatitis OBSERVATION Recurrent aphthous stomatitis (RAS) is a common cause of recurrent oral ulcers, which often leads to significant impairment of a patient’s quality of life. The underlying pathogenic mechanism remains unclear, and no treatment modality is uniformly effective. In this report, we describe the use of apremilast, an oral phosphodiesteras...

The aetiology of Behget's syndrome has long been disputed. Behget (1937) first suggested a viral hypothesis on the basis of finding inclusion bodies in scrapings from the ulcers. Sezer (1953, 1956) claimed to have isolated a virus from these patients and to have reproduced the disease, and showed a strongly positive complement-fixation reaction in other patients with Behget's syndrome. Evans et...

Oral ulcers are diverse in number. Recurrent aphthous ulceration is the most common form of painful ulcerations in oral cavity. The diagnosis is well defined but the etiology and pathogenesis remains unclear. It is common condition affecting 20% of general population. This review article provides the exact etiology, diagnosis, criteria and treatment of RAS.

Key Clinical Message The oral manifestations of EBV-positive mucocutaneous ulcers have a worrisome clinical appearance but relatively benign clinical course, responding well to conservative treatment. Elderly patients who develop an unexplained, persistent ulcer of the oral mucosa should have the lesion examined for EBV.

BACKGROUND Oral and genital ulcerations have been previously reported in 3 Navajo children diagnosed with severe combined immunodeficiency disease with T- and B-cell lymphopenia (T-B(-)-SCID). OBJECTIVE To evaluate the occurrence of oral and genital ulcerations in 12 Athabascan-speaking American Indians with a diagnosis of T-B(-)-SCID (SCIDA group) and to compare their occurrence in non-Athab...

Inflammation of the oral mucosa is a common and debilitating complication of chemotherapy that is preventable and manageable following health advices. Empowering the primary caregiver can be helpful in management of this condition. Aim: To determine the effect of empowering the caregivers on preventing inflammation of oral mucosa in children with cancer undergoing chemotherapy. Methods: This no...

Tuberculosis is caused by the Mycobacterium tuberculosis bacterium. Tuberculosis primarily affects the lungs. Patients mainly complain of cough, sputum, night sweating, weight loss, and fever. However, there may be cases of atypical presentations. Although aphthous mouth ulcers are mostly present in the oral cavity in primary tuberculosis patients, our literature search showed only one case rep...

conclusions to sum up, honey dressing with and without olive oil could successfully prevent the risk of amputation in case of diabetic foot ulcers. introduction as a common diabetic complication, foot ulcers may cause a huge burden both on the patient and healthcare system. the current study aims at investigating the effectiveness of honey dressing in the presence or absence of olive oil in dia...