introduction: the molecular mechanisms involved in pathogenesis of esophageal cancer have been the main concern of several studies. in this study, we aimed to investigate the changes of serum prooxidant-antioxidant balance (pab) value as a redox index, as well as serum c-reactive protein (crp) compared to healthy control group. materials and methods: in a cross-sectional study, blood samples we...

OBJECTIVE The aim of this study was to elucidate the etiology and treatment of primary ovarian insufficiency, which is of unknown cause in 95% of the cases. MATERIALS AND METHODS Thirty patients aged 18-40 years who presented to Dicle University Faculty of Medicine Clinic of Obstetrics and Gynecology between June 2012 and January 2014 and were diagnosed as having primary ovarian insufficiency...

BACKGROUND In the general population, reported levels of oxidative stress and antioxidant potential seem to vary. The aim of this study was to investigate the levels of oxidant status markers in relation to estimated glomerular filtration rate (eGFR) and albuminuria in Japanese population. METHODS Data were analyzed from 8335 individuals who underwent a general health screening test. For the ...

It is known that there a strong association between oxidative stress and insulin resistance in type 2 diabetes mellitus (T2DM). Although the role of glibenclamide treatment has been evaluated, only limited evidence about its antioxidant effects diabetic patients. Moreover, previous studies showed discrepant results regarding metformin on antioxidant/ oxidant parameters The present study aimed t...

objective: crocin, the carotenoid isolated from saffron, has numerous medicinal properties which include anticancer and antioxidant activities. some antioxidants, such as carotenoids, can act as pro-oxidants at higher dosages and therefore induce tissue damage. in this situation antioxidant defense systems in the liver activate to prevent tissue damage. this study investigates the possible toxi...

BACKGROUND AND OBJECTIVES Oxidant damage is an important contributor to the premature destruction of erythrocytes and anemia in thalassemias. To assess the extent of oxidant damage of circulating erythrocytes and the effects of antioxidant therapy on erythrocyte characteristics and anemia, we used a mouse model of human beta-thalassemia intermedia (b1/b2 deletion). DESIGN AND METHODS Several ...

The antitumour activities of extracts from the Red Sea seaweeds Jania rubens, Sargassum subrepandum, and Ulva lactuca were investigated in an in vivo mice model based on intramuscular injection of Ehrlich ascites tumour cells. In parallel, antioxidant activities were measured. Tumour marker levels, liver biochemical parameters, and hepatic oxidant/antioxidant status were measured to prove the a...

Depression is one of the prevalent psychiatric diseases in Turkey and world. Fluvoxamine a strong selective serotonin reuptake inhibitor (SSRI) that used as an antidepressant. No study investigating doses treatment may lead to disruption oxidant-antioxidant balance on cellular level addition its beneficial effects has been found literature. For this purpose, by creating application groups at 7....

BACKGROUND AND AIM: Recurrent Aphthous Stomatitis (RAS) as a common oral lesion can be related to oxidative stress. The aim of this study was to review the antioxidant-oxidant status of saliva in patients with RAS.METHODS: In this review study, all English and Persian articles were searched by relevant keywords from the PubMed, science direct, Cochrane, Scopus and Sid databases from 1995 ...