نتایج جستجو برای: pantoprazole sodium
تعداد نتایج: 188242 فیلتر نتایج به سال:
The present invention relates to multiple-unit tablet dosage forms, which is composed of several subunits (multiparticulates/pellets). Each small multiparticulate further composed of many layers. Some layer contains drug substance; others are rate controlling polymer. The resulting multiple-unit tablet dosage forms of pantoprazole were satisfactory fabricated. Pelletization technique has some a...
Pantoprazole is converted to its active form in the acidic canaliculi of the parietal cells when it inhibits the H, K-ATPase enzyme, i.e. the final stage in the production of hydrochloric acid in the stomach. The inhibition is dose-dependent and affects both basal and stimulated acid secretion. In most patients, freedom from symptoms is achieved in 2 weeks. As with other proton pump inhibitors ...
A 61-year-old male presents to the emergency room with complaints of fatigue, dizziness and bright red blood per rectum (BRBPR) for 2 days. Past medical history was significant for gastroesophageal reflux disease, non-steroidal anti-inflammatory drug (NSAID) induced ulcer, and end-stage renal disease (GFR < 30) status post 2 failed renal grafts. Pertinent medications include pantoprazole and so...
BACKGROUND/AIMS The effect of proton pump inhibitors (PPI) in Asian functional dyspepsia (FD) patients has not been well established as in Westerncountries. DA-9701, a novel prokinetic agent, stimulates gastric emptying and modulates visceral hypersensitivity in vivo and in human studies. This study was conducted to compare the efficacy of DA-9701 with a conventional PPI in mono or combination ...
STUDY OBJECTIVE To assess the effect of a prolonged continuous infusion of pantoprazole on patient outcomes when the drug was combined with standard octreotide therapy in patients with variceal hemorrhage. DESIGN Retrospective cohort study. SETTING Large academic hospital. Patients. One hundred thirty adults who received treatment for a documented variceal hemorrhage; 53 patients received s...
BACKGROUND Myocardial ischemia is inadequate perfusion due to reduced blood flow. Sudden onset of reperfusion could result with damage to the myocytes that have not been affected during ischemia called ischemia reperfusion (I/R) injury. Extracellular accumulation of H+ ions resulting in tissue acidosis is one of the underlying mechanisms. Inhibition of myocardial H+/K+-ATPase, namely proton pum...
Pantoprazole is a proton-pump inhibitor that is commonly prescribed for the treatment of gastroesophageal reflux-related disorders. Acute interstitial nephritis is an uncommon though important side-effect of these classes of drugs. We reported a case with acute interstitial nephritis due to pantoprazole. A 25-year-old woman from Ardabil was admitted to our hospital with the complaint of fever, ...
Clopidogrel is a mainstay therapy in the cardiovascular (CVS) pharmacology for the prevention of the stent thrombosis and myocardial infarctions following many different types of coronary syndromes.The conversion of clopidogrel; which is a prodrug, to its active metabolite is mediated by the cytochrome P450 (CYP).The CYP450 metabolic activation of clopidogrel has proposed about if the competiti...
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