I read the recent publication on paracoccidioidomycosis and cancer with great interest.(1) Rodrigues et al. concluded that a diagnosis of paracoccidiodomycosis increases the risk for lung cancer.(1) Indeed, there have been some previous reports on this issue. It is accepted that paracoccidioidomycosis can be an important overlapping infection in patients with cancer.(2) However, I have some com...

This study presents methodology for objectively quantifying the pulmonary region affected by emphysemic and fibrotic sequelae in treated patients with paracoccidioidomycosis. This methodology may also be applied to any other disease that results in these sequelae in the lungs.Pulmonary high-resolution computed tomography examinations of 30 treated paracoccidioidomycosis patients were used in th...

Paracoccidioidomycosis is the most common systemic mycosis in Latin America. Central nervous system (CNS) involvement described 10-27%. The objective to present two male patients with neuroparacoccidioidomycosis admitted Department of Internal Medicine National Hospital, one 2017 and other 2021. Both presented neurological symptoms improvement lesions amphotericin B. granulomas brain cells PCM ...

The disease is rare in childhood. In one study of 1,899 patients, 70 (3.68%) were less than 14 years and only 5 (0.26%) were below 7 years of age 2 . In our Institution, Universidade Federal do Paraná, 614 cases of paracoccidioi­ domycosis have been diagnosed. Among them there were 23 children (4.07%) aged less than 14 years. It is an essentially lymphatic disease in children, with additional g...

[This corrects the article DOI: 10.1371/journal.pone.0164745.].

Intramedullary lesions caused by Paracoccidioides brasiliensis have been rarely described. Its diagnosis may be challenging and surgical approach is indicated for diagnostic and therapeutic purposes. We hereby report a case with MRI and surgical findings in a 45 year-old woman with in t ramedul lary paracoccidioidomycosis, and make a review of other cases presented in the literature.

Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America, among immunecompetent patients. It's caused by the dimorphic fungus Paracoccidioiddes brasiliensis. Investigations regarding its immunopathogenesis are very important in the understanding of aspects related to natural history, as the protective immunity, and the relationship between host and parasite; also favoring ...