Paracoccidioidomycosis is a systemic mycosis of great epidemiological importance in Brazil and has significant impact on rural workers, mainly tropical subtropical regions. The disease transmitted via inhalation spores can cause severe manifestations. Ocular involvement uncommon, the differential diagnosis includes wide range other diseases, which make it difficult to identify condition. Treatm...

Introduction Paracoccidioidomycosis is a systemic mycosis endemic to Latin America, with frequent reports of poor treatment adherence resulting in worse clinical outcomes. The present study evaluated factors related patients paracoccidioidomycosis. Methods This cross-sectional included data from medical records paracoccidioidomycosis treated between 2005 and 2018 reference hospital southeastern...

Paracoccidioidomycosis is a systemic fungal infection caused by Paracoccidioides brasiliensis. As infectious diseases can cause DNA damage, the authors aimed at analyzing DNA breakage in peripheral blood cells of patients with paracoccidioidomycosis by using the comet assay. The results suggested that paracoccidioidomycosis does not cause genotoxicity. Key-words: Paracoccidioidomycosis. Paracoc...

Paracoccidioidomycosis is one of the most frequent systemic and endemic mycoses of Latin America caused by a dimorphic fungus. In AIDS patients, paracoccidioidomycosis appears as a severe and disseminated disease with a wide spectrum of clinical findings. The CD4 counts are usually less than 200 cell/mu L. We present a case of disseminated paracoccidioidomycosis with peripleuritis and subcutane...

F. Francesconi, MD A.C. Francesconi do Valle, MD, PhD M.T.T. Silva, MD, PhD R.L.B. Costa, MD, MSc E. Carregal, MD S. Talhari, MD, PhD Neurologic manifestations of paracoccidioidomycosis are uncommon. Generally, these are characterized by headache, seizures, or focal neurologic deficits due to a focal brain lesion. We describe a patient with subacute meningoencephalitis, CSF evidence of paracocc...

INTRODUCTION Paracoccidioidomycosis is a systemic infection caused by Paracoccidioides brasiliensis. METHODS In this study, a semi-nested PCR for paracoccidioidomycosis diagnosis was developed. The primers ITS1 and ITS4 were used in the first reaction, while the primers MJ03 and ITS1 primer were used in the second reaction. The semi-nested PCR was used to investigate biopsies of five patients...

Epidemiologic and clinical data for 53 patients with paracoccidioidomycosis and co-infected with human immunodeficiency virus (HIV) (cases) were compared with those for 106 patients with endemic paracoccidioidomycosis (controls). The prevalence of Paracoccidioides brasiliensis co-infection was estimated in 1.4% in cases of acquired immunodeficiency syndrome (AIDS). Patients co-infected with HIV...

The authors report a case of paracoccidioidomycosis misinterpreted as tuberculoid leprosy, both on clinical and histological examination. Sarcoid-like cutaneous lesion as the initial presentation is rare in young patient with paracoccidioidomycosis and can simulate other infectious or inflammatory diseases. On histology, tuberculoid granuloma presented similar difficulties. Treatment with dapso...

Paracoccidioidomycosis is an acute - to chronic systemic mycosis caused by fungi of the genus Paracoccidioides. Due to its frequent tegument clinical expression, paracoccidioidomycosis is an important disease for dermatologists, who must be up-to-date about it. This article focuses on recent epidemiological data and discusses the new insights coming from molecular studies, as well as those rela...

Paracoccidioidomycosis, the most prevalent deep mycosis in Latin America, is caused by dimorphic species of genus Paracoccidioides, affects predominantly male rural workers between 30-50 years age and an important cause morbidity mortality. It can present two clinical forms: acute/subacute or chronic. In rare cases paracoccidioidomycosis may simulate neoplasia must be considered as a differenti...