Sodium diklofenak adalah satu obat golongan NSAID non selektif dengan koefisien partisi sebesar 13,4, yang membuat penetrasi pada stratum korneum kurang optimal. Sehingga diperlukan bahan dapat membantu dalam meningkatkan penetrasi, salah satunya ialah menambahkan penetrant enhancer. Tujuan dari penelitian ini untuk melihat pengaruh penambahan mentol sebagai enhancer kadar 0; 0,5; 0,75; 1% terh...

Turbin Uap banyak digunakan pada Industri bidang pembangkit listrik. Rotor seringkali mengalami kerusakan dan diperlukan penggantian secara berkala. Pada penelitian ini, dilakukan analisis kualitas yang diproduksi dengan mesin CNC 5-Axis oleh PT XYZ sebagai salah satu bentuk Preventive Maintenance. Untuk memastikan sesuai spesifikasi, maka dua tipe pengujian NDT metode Penetrant Testing Dengan ...

Abstract Diffuse gliomas are aggressive brain tumors that lack effective therapies. Despite advances in the molecular characterization of gliomas, targeted treatments have failed to improve patient outcomes date. Here, we employed a functional genomics approach rapidly identify therapeutic vulnerabilities and provide strategy individualize treatment. Our process combined comprehensive genomic t...

Stumpy is a new chondrodystrophic mutant in the mouse. The condition is inherited as a fully penetrant Mendelian recessive, and is not allelic with brachymorphic, achondroplasia, or stubby-three similar, previously described mutants. No chromosomal position has yet been assigned to the gene. Phenotypically, stumpy mice are chondrodystrophic dwarfs with all cartilage-formed bones in the skeleton...

Received for publication 11 May 1979 and in revisedform 2 October 1979. 592 50% penetrant autosomal recessive model between the two types of families is compatible with a genetic dissimilarity between them. The high frequency ofthe Dw3 and Dw4 antigens, the Dw3/Dw4 genotype, and the decreased frequency of Dw2, however, indicate the existence of two or more important diabetic genetic factors ass...