نتایج جستجو برای: penetrant agent
تعداد نتایج: 254784 فیلتر نتایج به سال:
wild barley has invaded wheat fields ever since flamprop-isopropyl was outdated in iran. newly developed herbicides such as sulfosulfuron or sulfosulfuron plus metsulfuron-methyl can control it at higher than recommended dosages, but causing significant wheat injury. hence, two dose-response experiments were conducted to evaluate their efficacy when tank-mixed with thirteen different vegetable ...
N-Myristoyltransferase (NMT) represents a promising drug target within the parasitic protozoa Trypanosoma brucei (T. brucei), the causative agent for human African trypanosomiasis (HAT) or sleeping sickness. We have previously validated T. brucei NMT as a promising druggable target for the treatment of HAT in both stages 1 and 2 of the disease. We report on the use of the previously reported DD...
EGFR is a potent oncogene commonly altered in cancers including NSCLC and GBM. driven by canonical mutations can be treated inhibitors osimertinib. However, there an unmet need to treat tumors with acquired drug resistance C797S, or expressing non-canonical that are intrinsically resistant these agents. We have revealed how oncogenic GBM drive conformational structure promotes formation of cova...
In order to make full use of aged asphalt, a light oil regenerant for cold mixing was prepared in this paper, and the ratio regeneration effect studied through performance test recycled asphalt. The determined by 60 °C kinematic viscosity, mass loss before after aging, asphalt three indicators. thermogravimetric analysis four-component mechanical properties mixture were 15 splitting 20 compress...
Abstract Microtubule targeting agents (MTAs) are indispensable medicines to treat a wide range of cancers. While evidence suggests that glioblastoma (GBM) is sensitive disruptions in microtubule (MT) functions; most MTAs do not reach the brain. To address this limitation, we developed brain-penetrant MTA, ST-401, kills patient-derived GBM culture at nanomolar concentrations, binds colchicine si...
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