Total knee arthroplasty (TKA) has become one of the most common orthopedic surgical procedures performed nationally. As the population and surgical techniques for TKAs have evolved over time, so have the anesthesia and analgesia used for these procedures. General anesthesia has been the dominant form of anesthesia utilized for TKA in the past, but regional anesthetic techniques are on the rise....

OBJECTIVE The purpose of this study was to determine whether local analgesia at the incision site could reduce pain in women undergoing cesarean delivery or not. METHODS One hundred and four women undergoing cesarean deliveries were randomized in two groups according to 10 ml of 2% lidocaine (n = 52) or 0.9% saline (n = 52) was injected at the abdominal incision prior to the performance of th...

·T WO factors have increased interest in ketamine for postoperative analgesia. The first was the discovery of the N-Methyl-D-aspartate (NMDA) receptor and its role in central pain processing and spinal cord neural plasticity.1 Ketamine is one of two clinically useful NMDA receptor antagonists available (the other is dextromethorphan). Ketarnine binds non-competitively to the PCI, (phencyclidine...

1. Wu CL, Cohen SR, Richman JM, Rowlingson AJ, Courpas GE, Cheung K, et al. Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids. Anesthesiology 2005;103:1079-88. 2. Nishimori M, Ballantyne JC, Low JH. Epidural pain relief versus systemic opioid-based pain relief for abdominal aortic surgery. Cochran...