in a randomized, double blind study , we compared post operative pain and analgesic requirement in patients undergoing cesarean section with two types of general anesthesia: standardized general anesthesia (control group=26 cases) and preemptive low-dose ketamine (0.2 mg/kg) administered prior to anesthesia induction (keratmine group=27 cases). postoperative analgesia was provided for both grou...

Justificativa e Objetivos O controle da dor pós-operatória tem sido muito investigado nas últimas décadas, quando se verificou que a analgesia pós-operatória era inadequada. O termo “preemptiva” implica em uma forma de analgesia que, iniciada antes do estímulo doloroso ser gerado, previne ou diminui a dor subseqüente. Este estudo tem como objetivo uma atualização sobre analgesia preemptiva poss...

The aim of this study was to investigate the effects of preemptive analgesia on the inflammatory response and rehabilitation in TKA. 75 patients with unilateral primary knee osteoarthritis were conducted in this prospective study. All patients were randomly divided into two groups (MMA with/without preemptive analgesia group). The following parameters were used to evaluate analgesic efficacy: k...

introduction: several mehods have been proposed to alleviate pain after hysterectomy. pre-emptive analgesia has been used to relieve pain following abdominal hysterectomy with conflicting results. this study was performed to evaluate the efficacy of pre-incision skin infiltration of lidocaine in relieving postoperative pain in patients undergoing abdominal hysterectomy.  methods: 60 patients wi...

conclusions preemptive clonidine has many marvelous advantages over midazolam, including better sedation inside the operating room and then in the post-operative care unit, lower fentanyl doses are required during surgery, more stable heart rate and blood pressure are observed during the procedure, and patients report lower post-operative pain scores. objectives to compare the effect of preempt...

UNLABELLED BACKAGROUND AND OBJECTIVES: Since the finding that ketamine blocks NMDA receptors in the neurons of spinal dorsal horn, it has been used to inhibit or decrease central sensitization triggered by nociceptive stimulations. This study aimed at presenting pharmacological aspects of racemic ketamine and its levogyrous compound, as well as its usefulness for preemptive analgesia. CONTENT...

THE concept of preemptive analgesia to reduce the magnitude and duration of postoperative pain was paved in 1983 by Woolf, who showed evidence for a central component of postinjury pain hypersensitivity in experimental studies. Subsequently, an overwhelming amount of experimental data demonstrated that various antinociceptive techniques applied before injury were more effective in reducing the ...