background: because of the reported poor prognosis and absence of effective and specific therapeutic approaches, triple-negative breast cancer (tnbc) tumors have remained as an important area of investigations for clinicians and researchers. the aim of this study was to determine the clinical, pathological, histological, prognostic features, and outcome associated with this type of breast cance...

optic neuritis occurs in young patients, most often females, and presents as subacute monocular visual loss. periocular pain, particularly with eye movement occurs in the majority of cases. the retrobulbar form occurs in 65% of cases and is associated with normal optic disc appearance at onset. the central visual field is usually affected and an rapd and dyschromatopsia are present. brain magne...

abstract:   introduction: colorectal cancer (crc) is one of the most common cancers in the world. during the past decades, survival of colorectal cancer patients has improved worldwide, however, it is not clear what factors have contributed to this development. this study was designed to evaluate the prognostic impact of a wide spectrum of pathologic parameters on survival rate in patients with...

Introduction: 90% of the tumors in the head and neck are squamous-cell carcinomas (HNSCC), which have overall 5- year survival rate between 50% -60%. CD44 has been shown to be associated with the prognosis.  Materials and Methods: Biopsy specimens of 51 patients with oral tongue SCC were evaluated by Immunohistochemistry (IHC) for the CD44 antibody.  Results: There was no significant correlatio...

A total 119 physicians were interviewed to examine whether the diagnosis and prognosis of cancer should be communicated to terminally ill cancer patients. 53(44.5℅) of the physicians were not involved in the management of the patients who had recently died of cancer. 56(84℅) of the physicians who had patients didn't discuss the diagnosis and 62(93.9℅) the prognosis with their patients who had r...

context hepatocellular carcinoma (hcc) is a fatal disease. chronic hepatitis b virus (hbv) and/or hepatitis c virus (hcv) infection is the major cause of hcc. high viral replication rate and related hepatic/systematic inflammation are the major risk factors in hcc recurrence after hepatectomy or liver transplantation. evidence acquisition some of the carcinogenesis-related hbv mutations are als...

cutaneous metastases of rectal carcinoma is a rare event. it occurs in fewer than 4% of all patients with rectal cancer. when present, it typically signifies a disseminated disease with a poor prognosis. early detection and proper diagnosis of metastatic rectal cancer can significantly alter treatment and prognosis. we report a 70-year-old male who underwent rectal resection with permanent colo...