Currently, virus infections continue to be a public health problem, mainly affecting developing countries.1,2 According to the World Health Organization (WHO), infections by viruses such as HIV and hepatitis are among the 10 leading causes of death worldwide3 which entails a greater expenditure on health by the government. The preventive measures used in viral infections are mainly based on the...

Transcription factors play a crucial role in the regulation of cell behavior by modulating gene expression profiles. Previous studies have described a dual role for the AP-1 family transcription factor c-Jun in the regulation of cellular fate. In various cell types weak and transient activations of c-Jun N-terminal kinase (JNK) and c-Jun appear to contribute to proliferation and survival, where...

In molecular biology for cloning experiments, plasmid, a circular molecule is used as vector (carrier) to insert a desired gene or DNA fragment by ligating into it after digestion of both with the compatible restriction enzymes. Then by transforming with a host (generally E. coli) strain of desired traits the screening for appropriate clone is done. A plasmid is having selectable marker in the ...

A large number of applications such as querying sensor networks, and analyzing proteinprotein interaction (PPI) networks, rely on mining uncertain graph and hypergraph databases. In this work we study the following problem: Given an uncertain, weighted (hyper)graph, how can we efficiently find a (hyper)matching with high expected reward, and low risk? This problem naturally arises in the contex...

A high molecular weight protein phosphatase was purified from rabbit skeletal muscle displaying activity toward phosphorylase Q and synthase b isolated from the same tissue. The extensively purified enzyme was shown to have a M, = 260,000 by gel filtration and dissociated in sucrose density gradient centrifugations into a M, = 70,000 species. The 70,000-dalton enzyme form, resulting from prepar...

Pharmacognosy Research,2022,14,3,256-262.DOI:10.5530/pres.14.3.37Published:July 2022Type:Original ArticleAuthors:Abani Kumar Patar, Lakhon Kma, Jitul Barman, Shekhar Ghosh, and Taranga Jyoti Baruah Author(s) affiliations:Abani Baruah* Department of Biochemistry, Assam Royal Global University, Guwahati, Assam, INDIA. Abstract:Background: Naringenin (NGN) is a commonly available flavonoid in the ...

Motivation. Computational methods to predict protein–protein interactions are of great need. They can help to formulate hypotheses, guide experimental research and serve as additional measures to assess the quality of data obtained in high-throughput interaction experiments. Here, we describe a fully automated threestep procedure to predict and confirm protein–protein interactions. By maximisin...