BACKGROUND Control of the global burden of tuberculosis is obstructed due to lack of simple, rapid and cost effective diagnostic techniques that can be used in resource poor-settings. To facilitate the early diagnosis of TB directly from clinical specimens, we have standardized and validated the use of nested multiplex PCR, targeting gene fragments IS6110, MTP40 and 32kD α-antigen encoding gene...

We evaluated the usefulness of interferon-gamma release assays (IGRAs) in the diagnosis of active tuberculosis (TB) in routine clinical practice. We retrospectively assessed the diagnostic usefulness of the QuantiFERON-TB Gold In-Tube (QFT-IT) test in 519 consecutive patients who were suspected of having active pulmonary TB and had QFT-IT test results. Active pulmonary TB was diagnosed in 242 p...

STUDY OBJECTIVES Screening for pulmonary tuberculosis (TB) in war refugees entering low-prevalence countries for TB is a common policy, but workup strategies are difficult and expensive. DESIGN Prospective screening of war refugees for TB by chest radiograph and evaluation of the impact of additional polymerase chain reaction (PCR) testing for Mycobacterium tuberculosis complex (MTB) on clini...

C/101: Shukan Height, Near City Pulse Cinema, Ahmedabad Gandhinagar Highway, Gandhinagar, Gujarat. Pin:382421. Phone No:-+919426702404 Emai:[email protected] Individuals with HIV infection are at increased risk for tuberculosis (TB). The altered CD4 Tcell homeostasis induced by HIV infection may play a key role in the development of tuberculosis in HIV-infected patients. Among total 961...

BACKGROUND A high prevalence of tuberculosis (TB) in children presenting with severe pneumonia has previously been reported in South Africa. However, little is known about TB among children with pneumonia in Uganda and other resource limited countries. Moreover, TB is associated with high morbidity and mortality among such children. We conducted this study to establish the burden of pulmonary T...

BACKGROUND Diagnosis of pulmonary (PTB) and extra-pulmonary tuberculosis (EPTB) in smear-negative patients can be difficult. We assessed retrospectively the performance of Xpert MTB/RIF system (Xpert, Cepheid) in diagnosing smear-negative tuberculosis (TB), which represents the most common form of TB in a low incidence setting. METHODS Performance of Xpert was compared to acid-fast microscopi...

Background At present of the limitation of the current case finding strategies and the global urgency to improve tuberculosis (TB) case finding, a renewed interest in active case finding (ACF) has risen. World Health Organization (WHO) calls for research on TB screening among low-income countries because of the limitation of the passive case finding strategies. We aimed to evaluated Active Case...

Tuberculosis (TB) is a major cause of ill health in the world. The population infected by pulmonary TB worldwide estimated one-third population. transmitted droplets produced source. main goal prevention to prevent transmission other than curative purposes. preventive behavior can be affected several factors. This article aims review previous studies discussing correlation age and gender with TB.

Pulmonary Tuberculosis (TB) is a rare infectious complication after Hematopoietic Stem Cell Transplantation (HSCT), and may have different prognosis and clinical characteristics. Etiological basis of TB after HSCT is often difficult to discover, leading to difficulties in diagnosis. Here, we present two patients who were diagnosed with pulmonary TB after HSCT. One patient had non-Hodgkin's lymp...