Pyrethroid insecticides have been extensively used in China and worldwide for public health pest control. Accurate resistance monitoring is essential to guide the rational use of insecticides and resistance management. Here we examined the nucleotide diversity of the para-sodium channel gene, which confers knockdown resistance (kdr) in Culex pipiens pallens mosquitoes in China. The sequence ana...

Resistance to pyrethroids, the sole insecticide class recommended for treating bed nets, threatens the control of major malaria vectors, including Anopheles funestus Effective management of resistance requires an understanding of the dynamics and mechanisms driving resistance. Here, using genome-wide transcription and genetic diversity analyses, we show that a shift in the molecular basis of py...

With the exception of target site mutations, insecticide resistance mechanisms in the principle malaria vector Anopheles gambiae, remains largely uncharacterized in Burkina Faso. Here we detected high prevalence of resistance in Vallée du Kou (VK) to pyrethroids, DDT and dieldrin, moderate level for carbamates and full susceptibility to organophosphates. High frequencies of L1014F kdr (75%) and...

The efficacy of nets treated with lambda-cyhalothrin, a pyrethroid insecticide, on malaria infection and disease was assessed for the first time at the community level in Anopheles gambiae pyrethroid resistance areas. The study was carried out in northern Côte d'Ivoire, which is an area of kdr resistance. Four pairs of villages were selected and matched according to demographic, sociological, a...

From October 2000 to April 2001, insecticide bioassays were conducted in 18 ranches from 10 counties in the states of Mato Grosso and Mato Grosso do Sul, in Central Brazil. Horn flies from wild populations were exposed to diazinon-impregnated filter papers immediately after collection on cattle, and mortality was recorded after 2 h. A high susceptibility to diazinon was observed in all tested p...

Field populations of Triatoma infestans Klug were collected during 2002 from four villages in northern Argentina (El Chorro, La Toma, El Sauzal, and Salvador Mazza), after application of deltamethrin and other pyrethroids was ineffective. High levels of resistance to the pyrethroid insecticides deltamethrin, beta-cypermethrin, beta-cyfluthrin, and lambda-cyhalothrin were detected in all of the ...

an investigation was carried out on permethrin-susceptible and resistant strain of malaria vector, an.stephensi. efficacy of several pyrethroids such as permetrhrin, deltamethrin, lambdacyhalothrin, cypermethrin and cyfluthrin against this species showed that those with an α-cyano group and dibromo substitutions were more toxic to sensitive strains than the other classes like permethrin. the ra...

The convergent lady beetle (CLB), Hippodamia convergens (Guérin-Méneville), a species widely distributed and used in biological control, has exhibited high survival under field and laboratory conditions when treated with field rates of the pyrethroid k-cyhalothrin, a highly unusual phenomenon for a natural enemy. This work investigated and characterized the phenomenon of pyrethroid resistance i...

BACKGROUND Indoor residual spraying (IRS) with DDT has been the primary strategy for control of the visceral leishmaniasis (VL) vector Phlebotomus argentipes in India but efficacy may be compromised by resistance. Synthetic pyrethroids are now being introduced for IRS, but with a shared target site, the para voltage-gated sodium channel (VGSC), mutations affecting both insecticide classes could...

High levels of resistance to the major categories of insecticides, ie, organophosphorus, carbamates, pyrethroids, and DDT, have been detected in the diamondback moth in Taiwan. Synergist studies have provided insufficient evidence to show significant involvement of known metabolic systems, such as microsomal oxidation, esterase hydrolysis, and glutathione conjugation in organophosphorus and car...