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We study electrochemical p- and n-type doping in the well-known light-emitting polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV). Doping reactions are characterized using cyclic voltammetry. Optical measurements including photoluminescence and UV/Vis/NIR transmission were performed on doped samples. We find that oxidation in MEH-PPV is a highly reversible reaction resu...
BACKGROUND Metronidazole (MET) and Diloxanide Furoate (DF), act as antiprotozoal drugs, in their ternary mixtures with Mebeverine HCl (MEH), an effective antispasmodic drug. This work concerns with the development and validation of two simple, specific and cost effective methods mainly for simultaneous determination of the proposed ternary mixture. In addition, the developed multivariate calibr...
ion Matching Figure 3.1: Expertise Based Matching In this section we first introduce a model to semantically describe the expertise of peers and how peers promote their expertise as advertisement messages in the network. Second, we describe how the received advertisements allows a peer to select other peers for a given query based on a semantic matching of query subjects against expertise descr...
Meningoencephalic herniation (MEH) in the middle ear and mastoid is a rare pathological entity with possible life-threatening complications. We treated 24 patients with a trans-mastoid approach, and the bony defect was closed by heterologous materials positioned in a multilayer fashion. The cause of the bony defect were chronic otitis media with cholesteatoma, iatrogenic, spontaneous and post-t...
AIMS AND BACKGROUND The aim of this study was to investigate the relationship between EPHXI exon 3 Tyr113His and exon 4 His139Arg polymorphisms, predicted microsomal epoxide hydrolase (mEH) activity, and lung cancer development. mEH is a protective enzyme involved in oxidative defences against a number of environmental chemicals and pollutants, but it is also responsible for the xenobiotic acti...
Cytochrome P450 (P450, CYP), a major class of enzymes involved in Phase I drug metabolism, is expressed in the cellular endoplasmic reticulum together with other enzymes, such as microsomal epoxide hydrolase (mEH) and UDP-glucuronosyltransferase (UGT). In many cases, the metabolite produced by P450 is sequentially metabolized by other enzymes to increase its water solubility. It would be reason...
This study was performed to investigate the relationship between polymorphisms in microsomal epoxide hydrolase (mEH; Tyr113His and His139Arg substitution) glutathione S-transferase (GST; GSTM1 deletion, GSTT1 GSTP1.Ala114Val their correlation with clinico-histopathological features hepatocellular carcinoma (HCC).We evaluated environmental risk factors genetic alterations 556 individuals (86 cas...
the available minoxidil formulations for topical application suffer with major drawback having less contact time with the scalp which requires repeated application. hence, the present study was aimed to investigate the effect of microemulsions and microemulsion based hydrogel systems (mehs) for increased percutaneous penetration of minoxidil. minoxidil microemulsions were developed by following...
Integrated three-pulse stimulated echo peak shift data are compared for N,N-bis-dimethylphenyl-2,4,6,8perylenetetracarbonyl diamide and poly@2-(28-ethylhexyloxy)-5-methoxy-1,4-phenylenevinylene# ~MEHPPV! in toluene solvent. These two molecules represent a model probe of solvation dynamics and a prototypical soluble, electroluminescent conjugated polymer, respectively. The results indicate that ...
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