Introduction: Recent studies have shown the presence of Cl- channels in heart and liver mitochondrial membranes. In this work, we have characterized the functional profile of a Cl- channel from rat brain mitochondria. Methods: After removing and homogenizing the rat brain, the supernatant was separately centrifuged in MSEdigitonin, H2O and Na2CO3 and mitochondrial inner membrane vesicles wer...

Introduction: Different ATP-sensitive potassium channels have been detected in the mitochondrial inner membrane of cells. They are suggested to be involved in cell processes including cell protection. Here, we characterized the biophysical and electropharmacological properties of a KATP channel in the brain mitochondrial inner membranes. Methods: After removing and homogenizing the rat brain...

The Persian Gulf, a young and shallow epicontinental sea, is known for its unique geological oceanographic characteristics that foster diverse productive marine ecosystems. A substantial portion of the Gulf’s seafloor consists unconsolidated soft sediments, making it unsuitable colonization by many sessile organisms. Consequently, relatively few hard grounds submerged banks provide suitable hab...

Roughness elements or turbulence promoters have been widely used to enhance heat transfer in cooling passages of modern gas turbine blades. Although such ribs substantially enhance heat transfer, the heat transfer coefficient is reduced immediately at corner downstream of each rib, creating hot spots. To remove such hot spots some of the ribs can be detached from the channel walls. In this pape...

a b s t r a c t introduction: even today there is no effective drug therapy to prevent neuronal loss after brain stroke. in the present study we studied the effect of mitochondrial katp channel regulators on neuronal ultrastructure after ischemia reperfusion in the rat. materials & methods: rats temporarily subjected to four vessels occlusion for 15 minutes followed by 24 hours reperfusion with...

Thirteen repetitions of a cross-channel transect in the Khuran Channel within the Strait of Hormuz allowed the description of the mean flow and semidiurnal tidal properties of a north-south transect. Water velocity profiles were obtained with a 614.4 kHz TRDI Work Horse Broadband ADCP along this 3.3 km long transect on 10 October 2014, the third day of secondary spring tide. The M2, M4 and M6 f...

In this study, a periodic zigzag channel with rectangular cross-section has been used in order to obtain a high-efficiency system for cooling a polymer electrolyte fuel cell. An appropriate function of fuel cells and enhancement of their lifetime require uniform temperature conditions of around 80°C. On the other hand, due to volume and weight constraints, a low-density compact heat exchanger i...