two different growth media, namely complex and defined media, were used to examine establishment of steady-state conditions in phosphate-limited culture system of saccharomyces cerevisiae cen.pk113-5d strain. using the defined growth medium, it was possible to obtain steady state condition in the continuous culture. the effect of phosphate concentration on the growth of s. cerevisiae in phospha...

an analytical model for a coastal boundary current was used to investigate heat and salt budget of exchange flows in the persian gulf as a marginal sea. coastal boundary currents exchange heat and freshwater with the mosphere and the offshore waters. as heat and salinity fluxes caused by air-sea interaction and eddy activities, different temperature and salinity associated with boundary current...

several transporters appear to be important in transporting various drugs. many patients, who receive morphine as analgesic medication, also receive other medications with potency of changing morphine transport by affecting p-glycoprotein (p-gp) and oatp2 transport system. this could influence morphine pharmacokinetics and pharmacodynamics. the aim of present study was to elucidate the transpor...

BACKGROUND GPs have to respond to conflicting policy developments. As gatekeeper they are supposed to manage the growing demand for specialist services and as patient advocate they should be responsive to patients' preferences. We used an innovative approach to develop a referral guideline for patients with chronic knee pain that explicitly incorporates patients' preferences. METHODS A guidel...

The characteristics of patients with non-fatal road traffic injuries who received care from non-referral hospitals are described; an assessment of the difference between the characteristics of patients who received care at a referral hospital and those of patients who were treated at non-referral hospitals is made. A retrospective study, conducted in Chon Buri Province, Thailand, reviewed infor...

Background: The early diagnosis of idiopathic pulmonary fibrosis (IPF) has become increasingly important due to evolving treatment options. IPF patients experience a significant delay in receiving an accurate diagnosis, thus delayed access to tertiary care is associated with higher mortality independently from disease severity. Objective: The aims were to evaluate whether there had been a delay...

BACKGROUND Although under debate, routine screening for intimate partner violence (IPV) is recommended in health care settings. This study explored the utility of different screening and referral strategies for women exposed to IPV in primary health care. METHODS Using a randomized controlled trial design we compared two screening strategies (health care providers [HCP] versus audio computer-...

AIM To explore interpretations of "appropriate" and "inappropriate" elective referral from primary to secondary surgical care among senior clinical and non-clinical managers in five purposively sampled primary care trusts (PCTs) and their main associated acute hospitals in the English National Health Service (NHS). METHODS Semi-structured face-to-face interviews were undertaken with senior ma...

background: based on some estimation more than two million peoples in iran are affected by type 2 diabetes. the present study was designed to evaluate the status of diabetes control among type 2 diabetes patients in kurdistan, west of iran and its associated factors. methods: in our cross sectional study conducted in 2010, 411 type 2 diabetes patients were randomly recruited from sanandaj, capi...