Effective cancer pain management requires multidisciplinary approaches for multimodal analgesia. Although opioids have been the cornerstone, developments such as regional anesthesia and interventional pain techniques, complementary and alternative medicine, and new pharmaceuticals also have shown promise to relieve cancer pain. This overview of relevant clinical efforts and the modern day state...

Aim. To present main outputs of the International Scientific Conference on Brucellosis in South Eastern Europe (SEE) and Mediterranean Region, held in Struga, Republic of Macedonia, Nov. 12-14, 2009, and to summarize the weak points and constraints for implementation of the current brucellosis control programs in the SEE countries, as well as main components and directions for perspective devel...

In recent years, there has been a shift in the donor demographics with an increase in donation after circulatory death (DCD). Livers obtained from DCD donors are known to have poorer outcomes when compared to donors after brainstem death and currently only a small proportion of DCD livers are used. This review outlines the recent technological developments in liver DCD donation, including clini...

Abstract This article provides a comparative overview of phonological and phonetic differences Mukrī Kurdish varieties their geographical distribution. Based on the examined data, four distinct can be distinguished. In each variety area, different patterns are analyzed according to age, gender, social groups in order establish cross-regional cross-generational developments relation specific dis...

INTRODUCTION Uncomplicated urinary tract infection (uUTI) is a common reason for seeing a GP. In Denmark, it is debated if sulfamethizole or pivmecillinam should be recommended for empirical treatment of uUTIs. We evaluated sulfamethizole and pivmecillinam use in the five Danish regions from 2007 to 2011 and explored if the choice of antibiotic in primary care was in accordance with the regiona...

This study uses statistical analysis and trends to see the development of Degree Fiscal Decentralization, Ratio Regional Original Income Total Revenue, Autonomy Capacity Palangka Raya City during period 2008-2017 showing positive developments. Meanwhile, for degree between Tax Non-Tax Revenue Sharing, Contribution Assistance Needs showed negative results. situation shows that regional financial...

The emergence of East Asian regionalism is arguably one of the most important developments in the international relations of Asia. The trend began in 1997, when the region was hit by a massive economic crisis. The crisis undermined the credibility of regional institutions that were developed within a sub-regional or Asia-Pacific basis, namely the Association of Southeast Asian Nations (ASEAN), ...

Recent developments have made regional chemotherapy a more rational endeavour. The important pharmacokinetic principles have been defined. The increase in regional exposure achieved is a direct function of a drug's total body clearance and is an inverse function of the permeability-area product (defining ease of egress) for third spaces or of the regional arterial blood flow for intraarterial i...

PURPOSE OF REVIEW On the basis of the definition of high-risk soft tissue sarcomas and prognostic factors, the most recent developments of preoperative treatment strategies with special emphasis on regional hyperthermia combined chemotherapy are reviewed. RECENT FINDINGS The most important prognostic factors (e.g. size, grade, depth and resection margins) for localized soft tissue sarcomas ha...

Introduction The government is the first and most powerful decision-maker and actor in the field of spatial structure. Spatial structure is an essential part of the battle for control and protection of individuals and society. In fact, spatial planning and land use management is the manifestation of the government authority in the form of setting rules and allocating resources and decision-mak...