the objective of the present investigation was to assess the possible involvement ofgabaergic mechanism in analgesic effect of aqueous extract of origanum vulgare (org)in a rat model of acute pain test. sixty-three anaesthetized male wistar rats (200-250 g) werecannulated into the left ventricle. five to seven days after the recovery from surgery, org extractwas intraventricularly injected at d...

this paper presents results analyses of specific potential blowout scenarios for subsea oilpipelines between the coast of mainland of iran and khark island in the persian gulf. the analyses have been carried out with the sintef oil spill contingency and response (oscar) 3-dimensional model system.some hypothetical three-day blowout scenarios with light and heavy iranian oil have been investigat...

Estimation of item response model parameters and ability distribution parameters has been, and will remain, an important topic in the educational testing field. Much research has been dedicated to addressing this task. Some studies have focused on item parameter estimation when the latent ability was assumed to follow a normal distribution, whereas others have utilized nonparametric or semipara...

Inflammation is portion of the body's immune response and it is basically a host protective response to tissue ischemia, injury, autoimmune responses or infectious agents. Although the information presented so far points to a detrimental role for inflammation in central nervous system (CNS) disease, it may also be useful. CNS demonstrates characteristic of inflammation, and in response to damag...

Traumatic brain injury (TBI) is a common cause of death which affects millions of people around the world. TBI is also associated with various neurological impairments. After the primary mechanical injury at the moment of a TBI event, several cellular and molecular processes are activated within the brain tissue as the secondary injury. An important mechanism involved in the secondary injury of...

environmental pollution by 2,4-dicholorphenol (2,4-dcp), commonly found in industrial wastewater has been a concern for humans over the past 50 years. garden radish peroxidase (grp) can eliminate this poisonous pollutant. the aim of this study was to apply an experimental response surface methodology (rsm) and central composite design (ccd) to optimize grp-based treatment in order to maximize ...