The use of generic medicines is widely advocated as a means of reducing healthcare costs. Generic drugs need to meet bioequivalence specifications but, with epilepsy, there is concern that permitted differences in bioavailability may be sufficient to allow loss of seizure control or toxicity in susceptible patients. Where generics are dispensed, whether in response to a generic prescription or ...

Introduction: There is evidence that diabetes affects seizure susceptibility. Ginger (Zingiber officinale Roscoe) which is used in traditional medicine has antioxidant activity and neuroprotective effects. The aim of this study was to evaluate the seizure threshold induced by pentylenetetrazole (PTZ) in diabetic mice after induction of diabetes with streptozocin and to examine the possible ...

how to cite this article: tavasoli ar, gharib b, alizadeh h, farshadmoghaddam h, memarian s, ashrafi mr, sharifzade m. brain on fires: super refractory seizure in a 7 year old boy. iran j child neurol. autumn 2016; 10(4):80-85. abstract we present a 7 year old boy afflicted with super-refractory seizure that responded poorly to antiepileptic drugs and sustained a long course of hospitalization ...

INTRODUCTION Although one third of febrile seizures are complex, a consensus has still not been reached on how to manage them, as is the case with simple febrile seizures. The objective of this study is to estimate the usefulness of complementary examinations and the risk of associated serious intracranial pathology. PATIENTS AND METHODS A retrospective review was conducted from 2003 until 20...

background:tramadol poisoning has increased in recent years. seizure is one ofthe side-effects oftramadol toxicity. there is a controversy about possible preventive effect of naloxone in tramadol poisoning induced seizure. therefore, this study was performed to compare seizure incidence in tramadol poisoning patients who received and did not receive naloxone, as an opioid antagonist. methods:th...

introduction: seizures are symptoms associated with abnormal electrical activity in electroencephalogram (eeg). the present study was designed to determine the effect of absence seizure on heart rate (hr) changes in electrocardiogram (ecg). methods: hr alterations were recorded simultaneous with spike and wave discharges (swd) by eeg in 6 wag/rij rats as a well characterized and validated genet...

post-traumatic epileptic seizure is a common complication of brain trauma including military injuries. we present clinical characteristics and correlates of post-traumatic epilepsy in 163 head-injured veterans suffering from intractable epilepsy due to blunt or penetrating head injuries sustained during the iraq-iran war. the medical records of 163 war veterans who were admitted by the epilepsy...