The present review provides an update on endocannabinoid basic science and clinical studies and proposes a new model to describe reciprocal interactions between somatic dysfunction and the endocannabinoid system. The endocannabinoid system consists of cannabinoid receptors, endogenous ligands, and ligand-metabolizing enzymes. The system exemplifies the osteopathic principle that the body posses...

The introduction of self-healing capabilities to software systems could offer a way to alter the current, unfavorable imbalance in the software security arms race. Consequently, self-healing software systems have emerged as a research area of particular interest in recent years. Motivated by the inability of traditional techniques to guarantee software integrity and availability, especially aga...

The term and characteristic of self-healing, applied to systems, is often seen from different fields of computer science, such as fault tolerance or network and service management, with diverging semantics. Since this impression was confirmed also during the first discussions of the Dagstuhl seminar on ”Self-Healing and Self-Adaptive Systems”, a seminar’s working group on ”Terminology” was form...

In recent years, several network online algorithms have been studied that exhibit self-x properties such as self-healing or self-adaption. These properties are used to improve systems characteristics like, e.g., fault-tolerance, reliability, or load-balancing. In this paper, a symbolic reliability analysis of self-healing networked embedded systems that rely on self-reconfiguration and self-rou...

Industrial Control Systems (ICSs) are computers managing many critical infrastructures like power plants, aeroplanes, production lines, etc. While ICS were specialised hardware circuits without internet connection in former times, they are nowadays commodity computers with network connection, TCP/IP stack, and a full operating system, making them vulnerable to common attacks. The defensive mech...

Given increasing environmental and energy issues, mimicking nature to confer synthetic materials with self-healing property to expand their lifespan is highly desirable. Just like human skin recovers itself upon damage with the aid of nutrient-laden blood vascularization, designing smart materials with microvascular network to accelerate self-healing is workable but continues to be a challenge....

Current embryonic attempts at software self–healing produce mechanisms that are often oblivious to the semantics of the code they supervise. We believe that, in order to help inform runtime repair strategies, such systems require a more detailed analysis of dynamic application behavior. We describe how to profile an application by analyzing all function calls (including library and system) made...

Our approach to creating self-healing systems is based on software architecture, where repairs are done at the level of a software system's components and connectors. In our approach, event-based software architectures are targeted because they offer significant benefits for run-time adaptation. Before an automated planning agent can decide how to repair a self-healing system, a significant inf...

Automated intrusion prevention and self-healing software are active areas of security systems research. A major hurdle for the widespread deployment of these systems is that many system administrators lack confidence in the quality of the generated fixes. Thus, a key requirement for future self-healing software is that each automatically-generated fix must be validated before deployment. Under ...