a reliable, rapid and accurate method based on spiked calibration curves and direct sample introduction was developed for determination of 17 pesticide residues in rice by gas chromatography-mass spectrometry single quadrupole selected ion monitoring gc/ms-sq-sim. sample preparation is based on extraction with acetonitrile without clean up. the use of spiked calibration curves for constructing ...

A test battery for identifying ecotoxicological hazards was applied to six pharmaceuticals (carbamazepine, diclofenac, ethinylestradiol, ibuprofen, propranolol, and sulfamethoxazole), to their mixtures, and to urine spiked with pharmaceuticals to test the suitability of biotests for screening urine and wastewater and for monitoring the efficiency of wastewater treatment. The test battery compri...

This paper evaluates the potential of 3D printing, a semi-automated additive prototyping technology, as a means to design and prototype a sample-to-device interface, amenable to diagnostics in limited-resource settings, where speed, accuracy and user-friendly design are critical components. As a test case, we built and validated an interlock meter-mix device for accurately metering and lysing h...

a user-friendly and inexpensive ionic liquid-based single-drop microextraction (il-sdme) method was developed to preconcentrate trace amounts of aminophenol isomers (aps) from human urine, hair dye and water samples prior to analysis by high performance liquid chromatography-ultraviolet spectrophotometry detection (hplc-uv). under optimum conditions (i.e., 3.5 µl of 1-hexyl-3-methylimidazolium ...

Coumaphos is an organophosphorus compound used as insecticide and frequently by beekeepers for the management of parasitic mites. The most important metabolite, chlorferron (CFN), has been identified in biological samples foodstuff. need to quickly identify presence typical metabolites, indication interaction with coumaphos driven produce a highly sensitive electrochemical method analysis, base...

A method for the determination of six organochlorine pesticides in human serum is proposed. Serum samples containing in vitro spiked pesticides (alpha-HCH, beta-HCH, gamma-HCH, p,p'-DDE, o,p'-DDT, and p,p'-DDT) were used to evaluate the method. The method involved pesticide extraction from a serum-silica suspension with n-hexane-acetone (9:1), extract purification using alumina-column chromatog...

OBJECTIVES Cyclophosphamide (CP) and ifosfamide (IF) are effective anti-cancer drugs but their genotoxicity can harm everyone contacting them occupationally or environmentally. Therefore, a sensitive method for monitoring their amounts in biological and environmental samples is needed. This has aimed to develop a method for analyzing these drugs in urine and water sewage samples. MATERIAL AND...

A new simple, cheap, and rapid method to increase the sensitivity of pencil graphite electrode (PGE) determine Linagliptin (LNG) was developed by modified PGE with copper microparticles (Cu-PGE). The disposable sensor electrode's preparation depended on electrodeposition Cu-microparticles that can be applied for determined LNG complexed it Cu+2 ions measure LNG-Cu complex onto Cu-PGE improved. ...

We describe two methods for the quantitative analysis of apalcillin and its metabolites in serum and urine by reverse-phase high-pressure liquid chromatography (HPLC), a fast isocratic method for the parent drug, and a gradient method that allows the simultaneous assay of two metabolites. Serum was deproteinized with acetonitrile, and urine was diluted with buffer solution. The detection limit ...