Nerve regeneration is a complex biological phenomenon. In the peripheral nervous system, nerves can regenerate on their own if injuries are small. Larger injuries must be surgically treated, typically with nerve grafts harvested from elsewhere in the body. Spinal cord injury is more complicated, as there are factors in the body that inhibit repair. Unfortunately, a solution to completely repair...

Spinal cord injuries (SCI) can be caused by direct injuries such as car accidents, falls, and sports injuries and also by indirect injuries such as diseased tissue that surrounds and affects the spinal cord [1]. 12,000 new SCI cases are reported in the US every year and there are estimated to be up to 327,000 people in the US currently living with a SCI [1-2]. In 2008, a study was performed whe...

UNLABELLED SUBAXIAL CERVICAL FACET DISLOCATION INJURIES: STANDARDS There is insufficient evidence to recommend treatment standards. GUIDELINES There is insufficient evidence to recommend treatment guidelines. OPTIONS Closed or open reduction of subaxial cervical facet dislocation injuries is recommended. Treatment of subaxial cervical facet dislocation injuries with rigid external immobil...

  Background :Cell-based therapies can be used to treat neurological diseases and spinal cord injuries. The aim of this study was to assess the clinical outcome of bone marrow derived mononuclear cells (BM-MNCs) transplantation in patients with spinal cord injuries.   Method s: Following a systematic review to detect clinical intervention studies, a meta-analysis was done for pooling data to es...

objectives major differences exist in the anatomy and biomechanics of the growing spine that causes failure patterns different from those in adults. spinal injury in the pediatric patient is a main concern because timely diagnosis and appropriate treatment can prevent further neurologic damage and deformity and potentiate recovery. we conducted a retrospective clinical study of 137 cases (93 bo...

BACKGROUND Despite the significant morbidity and mortality associated with all-terrain vehicle (ATV) use in children, their use continues to increase dramatically. To determine the frequency and impact of spinal fractures in children and adolescents injured in ATV accidents, we reviewed all 4 of the available Kids' Inpatient Databases. METHODS The Kids' Inpatient Databases (http://www.ahrq.go...

Background Motocross is a form of motorcycle racing held on established off-road circuits and has been a recreational and competitive sport across the world for >100 years. In the United Kingdom alone, motocross has grown into a phenomenally ambitious and popular franchise. There are >200 motocross clubs across the country, permitting >900 events annually. Purpose To assess the current trend ...

background: spinal cord has a limited capacity to repair therefore, medical interventions are necessary for treatment of injuries. transplantation of schwann cells has shown a great promising result for spinal cord injury (sci). however, harvesting schwann cell has been limited due to donor morbidity and limited expansion capacity. furthermore, accessible sources such as bone marrow stem cells ...

INJURY to the spinal cord is devastating and catastrophic. Its unfortunate sequelae have been recognized since early Egyptian times [l]. Since damage to the spinal cord almost always results in permanent loss of sensory and motor functions below the level of the injury, the best solution to the problem of spinal cord injuries is prevention. There are no published data on the incidence of trauma...

Internal fixation of traumatic spinal injuries has been associated with spinal canal stenosis, spinal cord compression, and nerve root impingement. We present a case of spinal cord/cauda equina compression due to migration of intact, anchored thoracolumbar Luque rods into the spinal canal through a laminectomy defect, leading to neurologic complications 10 years after the original operation.