1. A pneumotropic virus which forms elementary bodies has been isolated from apparently normal albino Swiss mice. 2. The antigenic relationship of this virus to those of meningopneumonitis, lymphogranuloma venereum, hamster pneumonia (7), and human pneumonitis (8) was established either by cross-immunity or complement fixation or both. 3. In spite of a relationship to other viruses, the virus c...

Living organisms are continuously exposed to a wide variety of oxidative radicals. Therefore, there is a constant demand for exogenous antioxidant supply. In this regard, one of these exogenous antioxidants with well established potency, quercetin has been utilized in various formulations. Yet due to its poor water solubility, its extensive applications are limited so far. In this study, TiO2 n...

OBJECTIVE Certain dietary constituents can induce toxicity and play a critical role in the development of several hepatic disorders. Tartrazine, metanil yellow and sunset yellow are widely used azo dyes in food products, so the present study is aimed to investigate the food color induced hepatotoxicity in Swiss albino rats. MATERIALS AND METHODS Swiss albino rats were divided into four groups...

BACKGROUND Desvenlafaxine is used as an antidepressant and acts by inhibiting reuptake of serotonin and nor-adrenaline. PURPOSE The safety profile of desvenlafaxine has not yet been established during pregnancy, so we planned this study to see the behavioral changes in pups of mice who received desvenlafaxine during gestational period. METHODS Swiss albino mice were used for the present stu...

β-Cyfluthrin, is a broad-spectrum type II synthetic pyrethroid insecticide. People are exposed to cyfluthrin by consuming contaminated food and from residues persisting after indoor or outdoor applications of cyfluthrin containing products. The aim of this study was to evaluate the neurobehavioral toxicity of cyfluthrin after oral administration to Swiss albino mice. Male weanlings (21 days old...

the aim of this study was to evaluate antitumour activity of the roots of hibiscus tiliaceus linn. against dalton’s ascitic lymphoma (dal) in swiss albino mice. a significant enhancement of mean survival time (mst) of h. tiliaceus treated tumour bearing mice was found with respect to control group. h. tiliaceus treatment was found to enhance peritoneal cell counts. when these h. tiliaceus treat...

BACKGROUND It is known that following chronic dosing with bupropion HCl active metabolites are present in plasma at levels that are several times higher than that of the parent drug, but the possible convulsive effects of the major metabolites are not known. METHODS We investigated the convulsive liability and dose-response of the three major bupropion metabolites following intraperitoneal ad...

Nutmeg, the dried seed kernel of Myristica fragrans, MF (Family: Myristicaceae) possesses antifungal, hepatoprotective and antioxidant properties. Its radioprotective effect against 6, 8 and 10 Gy gamma radiation was evaluated by 30 day survival assay. Regression analysis yielded LD(50/30 )as 6.83 Gy and 8.89 Gy for irradiated only and (MF + radiation) groups, respectively. The dose reduction f...