Background. Achieving reproducibility in research design is challenging when patient cohorts under study are inconsistently defined. Traditional Chinese medicine (TCM) diagnosis is one example where inconsistency between practitioners has been found. We hypothesise that the use of a validated instrument may improve consistency. Biochemical biomarkers may also be used enhance reliability. Method...

Zheng is the basic theory and essence of traditional Chinese medicine (TCM) in diagnosing diseases. However, there are no biological evidences to support TCM Zheng differentiation. In this study we elucidated the biological alteration of cirrhosis with TCM "Liver-Kidney Yin Deficiency (YX)" or "Dampness-Heat Internal Smoldering (SR)" Zheng and the potential of urine metabonomics in TCM Zheng di...

Traditional Chinese medicine (TCM) has long been used for patients with psoriasis. This study aimed to investigate TCM usage in patients with psoriasis. We analyzed a cohort of one million individuals representing the 23 million enrollees randomly selected from the National Health Insurance Research Database in Taiwan. We identified 28,510 patients newly diagnosed with psoriasis between 2000 an...

The relationship between disease, syndrome and formula is thought to be one of the most significant problems in TCM clinical and basic practice presently. Generally speaking, syndrome is not only the core of TCM basic theory and syndrome differentiation, but also the bridge linking disease and formula, and the base of definite diagnosis and proper treatment [1]. However, it was pointed out rece...

Objective: This study aims to systematically review the efficacy of Traditional Chinese Medicine (TCM) for treatment of dry eye symptom (DES). Methods: PubMed, EMbase, MEDLINE, The Cochrane Library, VIP, CNKI, CBM and Wanfang databases were searched manually and automatically by computer. The published literatures about DES treated by TCM were collected. After selection, quality evaluation and ...

Traditional Chinese medicine (TCM; zhōng yī) syndrome groups are based on the symptoms of human diseases and guide the use of Chinese herbs. The aim of this study was to examine the effects of TCM syndrome groups on biochemical characteristics and quality of life (QOL) in women with metabolic syndrome (MS). Among the 1080 registered female patients screened at our outpatient clinic, a total of ...

Systems biology is considered to be the possible technology that could bring breakthroughs in the study of TCM (traditional Chinese medicine). Proteomics, as one of the major components of systems biology, has been used in the mechanistic study of TCM, providing some interesting results. In the present paper, we review the current application of proteomics in the mechanistic study of TCM. Prote...

As an important component of traditional medicine, Traditional Chinese Medicine (TCM) is widely spread and applied in more than 100 countries across the world. The standardization of TCM is very important for the international application of Chinese medicine. In this paper, we have explained and analyzed the standardization situations of TCM in China with the purpose of providing reference for ...

Background Former findings suggested that MTX-based combination therapies show improved efficacy and safety compared to monotherapy [1] . Several studies [2] have been conducted analysis on therapies, but there is a lack of systematic involving MTX+TCM (Traditional Chinese medicine) therapies. Objectives To assess the effectiveness adverse events Methotrexate-based (MTX-based) therapies(especia...