the incorporation of 3H-thymidine by 5 0 % (IC50) at a dose of 2.6 X 10~4 M in L 1210 and at a dose of 6 X 10~4 M in P 388 murine leukemias. On the basis of cell fractionation studies, compound 2 was found to bind about equally to the cell nuclei, microsomes, and mitochondria. ESR experiments indicate different degrees of immobilization of the label in various fractions. The efficiency of bindi...

Indonesia, with abundant diversity, encompasses a diverse array of ethnicities, cultures, languages, and religions, presenting both advantages vulnerabilities. Exploiting these diversity religious factors, extremist groups disrupt national harmony due to lack proper understanding doctrine. The escalating intolerance fanaticism, particularly in Java, pose clear imminent threat, resulting violati...

Congestion on roads results in infrastructural deficiencies including massive delays, greater fatalities, and enhanced mental stresses, reduced transit efficiency, increased travel costs. Traffic is a major problem specifically the central area of Lahore city. This study aimed at understanding traffic congestion from stakeholders' perspective suggesting mitigation measures. A sample 365 respond...

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Following the recognition that N-ethylene-substituted phosphoramides possess tumor-inhibitory properties against transplanted tumors in animals (cf. 8), there have been a number of clinical studies reported in the literature (1-6, 11-13). These have usually dealt with the action of TEPA and thioTEPA primarily against leukemias. OPSPA itself has undergone extensive clinical evaluation against so...

In previous studies’ we have instilled cytotoxic agents and metabolic depressants into the endometrial cavity of rats, and have thereby induced changes in the endometrium which have resulted in reduced fertility. It was suggested that this reduction of fertility was due to an endometrial environment which was inadequate for implantation. Two different types of histologic changes have been obser...

The administration of t ryptophan or cortisone to rats bearing the Morris 5123 Hepatoma resulted in significant increases in t ryptophan pyrrolase activity in the host liver but in no change in the low tryptophan pyrrolase activity of the neoplasm. The repressed level of this enzyme in the neoplasm was not a result of the lack or excess of cofactors or enzymes necessary for the assay procedure ...

In this study, amino group surface-functionalized porous silicon adsorbent was successfully prepared for the first time using diamond wire saw powder (DWSSP) as raw material through copper-assisted chemical etching (Cu-ACE) and organic functional grafting. Amino-functionalized (TEPA-GTS-NPSi) can be used removing As(V) from water. The properties mechanism of new were characterized by infrared s...

Poultry products are comparatively rich in cholesterol. WHO report indicates incidence of coronary heart disease and high dietary cholesterol level to be positively correlated. In such a situation, decreasing the cholesterol content in poultry products would be appropriate. Onion and garlic are ascribed with therapeutic effects such as hypocholesterolemia, hypolipidemia and immunosuppressant ac...