BACKGROUND The impact of total serum cholesterol as a risk factor for cardiovascular disease decreases with age, which casts doubt on the necessity for cholesterol-lowering therapy in the elderly. We assessed the influence of total cholesterol concentrations on specific and all-cause mortality in people aged 85 years and over. METHODS In 724 participants (median age 89 years), total cholester...

The effects of cholesterol dosage, cortisone, and desoxycorticosterone acetate on total serum cholesterol, lipoproteins, and atherosclerosis were studied over a period of 112 days in thirty-two rabbits. Cholesterol was administered by feeding the rabbits diets containing 0.063, 0.25, and 1.0 per cent cholesterol At intervals measurements were made of total serum cholesterol and of low density l...

the effects of three ficus carica leaf extracts on the total cholesterol levels (tc) of serum and liver were investigated in experimentally-induced nutritional hyperlipidemic rats. in nine treatment groups (n=5 each group), hyperlipidemic rats were treated daily with hydromethanolic (total) extract (2.5, 5, 10 mg/kg, intraperitoneal [ip]) and its aqueous fractions, namely fraction a (10, 50, 25...

100 patients s uffering f rom myocardial i n f a r cti on we r e t ested i n various hos p itals, f o r cho l ester o l , t r iglyceride , and t otal lipid . method s f or choleste r o l , triglyce ride a nd total lipid tests , as wel l as the ir norma l ranges e xpl ained . spe cifi cations of pa t i ents were compi l e d a s f a r as poss ible and i n table no.1, a comparison has be en g i ve...

BACKGROUND AND OBJECTIVES The inhibition of cholesterol absorption by ezetimibe increases cholesterol synthesis. The effect of inhibition of cholesterol synthesis on cholesterol absorption is controversial. The influence of these interactions on cholesterol levels is unknown. We investigated on the extent to which cholesterol levels were affected by the reaction of one pathway to the inhibition...

The effects of feeding cholesterol, sitosterol, and lovastatin on cholesterol absorption, biosynthesis, esterification, and LDL receptor function were examined in the rat jejunal mucosa. Cholesterol absorption was measured by the dual-isotope plasma ratio method; the rate-limiting enzyme of cholesterol biosynthesis, 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, was measured as tota...

OBJECTIVE To determine the quantitative importance of dietary fatty acids and dietary cholesterol to blood concentrations of total, low density lipoprotein, and high density lipoprotein cholesterol. DESIGN Meta-analysis of metabolic ward studies of solid food diets in healthy volunteers. SUBJECTS 395 dietary experiments (median duration 1 month) among 129 groups of individuals. RESULTS Is...

Thyroid hormone withdrawal (THW) for postoperative radioiodine adjuvant therapy or diagnostic radioiodine whole body scan in patients with differentiated thyroid cancers results in acute thyroid hormone deficiency and abnormal lipid profiles. To better clarify the clinical pattern of dyslipidemia occurring after THW, we retrospectively analyzed the association between serum total cholesterol le...