The chloroplast envelope is a continuous boundary of two osmiophilic membranes and has an important role in galactolipid synthesis [ 11. It was interesting to determine whether the envelope is the site of synthesis of other lipid components in the chloroplast. We have chosen a-tocopherol for these experiments because it represents >40% of the total prenylquinones of the chloroplast [2]. The bio...

Background: Aging is associated with attenuation of immune responses. Studies show that old people are vulnerable to infectious diseases such as influenza. α-Tocopherol as an immunomodulator affects immune responses. In the present study, the effect of α-tocopherol, on lymphocyte responses i.e. interferon-gamma (IFN-γ), Tumor Necrosis Factor-alpha (TNF-α), and nuclear factor-κB (NF-κB)  in elde...

The oxidative modification of low density lipoprotein (LDL) may play an important role in atherogenesis. Antioxidants that can prevent LDL oxidation may act as antiatherogens. Our understanding of the mechanism of LDL oxidation and factors that determine its susceptibility to oxidation is still incomplete. Copper is a candidate for oxidizing LDL in atherosclerotic lesions. The binding of copper...

We report a fast, simple high-performance liquid-chromatographic assay for serum alpha-tocopherol, with use of a reversed-phase column and tocol as internal standard. Only 200 microliter of serum is required. Isocratic elution of the n-hexane extract is done within 6 min; total analysis time is less than 1 h. Within-day precision (CV) was 2.3% for 24 samples of a normal plasma pool (mean concn,...

serum alpha-tocopherol of98(62 male and 36 female) cancer patients and 30 (13 male and 17 female) control healthy subjects was investigated. the cancer patients showed a significantly low level of alpha-tocopherol as compared to control healthy subjects. also, significantly higher levels of serum alpha-tocopherol were found in complete remission patients as compared to the partial response pati...

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The study was aimed at evaluating the antioxidant activity of hydroalcoholic solution extracts of Urtica dioica L. (UD), Malva neglecta Wallr. (MN) plants and their mixture. In this study, flower (UDF), root (UDR), seed (UDS) and leaf (UDL) parts of UD and flower (MNF) and leaf (MNL) parts of MN were used. The antioxidant properties of hydroalcoholic extracts and their mixture were evaluated us...

Postabsorptive elimination of the various forms of vitamin E appears to play a key role in regulation of tissue tocopherol concentrations, but mechanisms of tocopherol metabolism have not been elucidated. Here we describe a pathway involving cytochrome P450-mediated omega-hydroxylation of the tocopherol phytyl side chain followed by stepwise removal of two- or three-carbon moieties, ultimately ...

The weight, height, body mass index (BMI), waist/hip ratio, serum retinol and alpha-tocopherol and lipid profiles of 16 overweight (BMI > or = 25.0 kg/m2) Thai males and 56 overweight females, compared with 14 males and 58 females in a control group (BMI 18.5-24.9 kg/m2), were investigated. Subjects for the study were those persons who turned up regularly for physical check-up at the Outpatient...

This study investigated some quality attributes of the functional properties turmeric rhizome flour cultived in Côte d’Ivoire. It consisted comparing powder with film (PWF) and without (PWAF) to identify nutritionally technologically appropriate uses. In terms properties, PWAF had best water absorption rates (1032.156 ± 34.016%), stability (74.3%), solubility index (19.50%) very good wettabilit...