Structural equation modeling (SEM) has been used in a wide range of applied sciences including genetic analysis. The recently developed R package, strum, implements a framework for SEM for general pedigree data. We explored different SEM techniques using strum to analyze the multivariate longitudinal data and to ultimately test the association of genotypes on blood pressure traits. The quantita...

the objective of this study was to analyze the association of somatic cell score (scs) with milk, fat and protein yields across parities. records of production traits and somatic cell counts (scc) from first, second and third parity that were collected by the animal breeding center of iran from 1993 to 2010 were used.all animals were grouped into six classes according to scc and production trai...

Genome-wide Association Study Related to Semen Traits Based on Gene-set Enrichment Analysis in Holstein Bulls

Background: The Osteopontin (OPN) is a highly phosphorylated glycoprotein in numbers of bovine tissues and milk. OPN has been reported to be associated with milk production in cattle. Objective: The genotype and allelic frequencies for OPN and its association with milk production will be evaluated in Iranian Holstein Bulls.   Materials and Methods: Bulls DNA (100) was isolated. Oligo was used f...

Dioecy is reported to be correlated with a number of ecological traits, including tropical distribution, woody growth form, plain flowers, and fleshy fruits. Previous analyses have concentrated on determining whether dioecy is more likely to evolve in lineages possessing these traits, rather than considering the speciation and extinction rates of dioecious lineages with certain combinations of ...

Plant development is remarkably plastic but how precisely can the plant customize its form to specific environments? When the plant adjusts its development to different environments, related traits can change in a coordinated fashion, such that two traits co-vary across many genotypes. Alternatively, traits can vary independently, such that a change in one trait has little predictive value for ...

OBJECTIVES We explain why traits of interest to behavioral scientists may have a genetic architecture featuring hundreds or thousands of loci with tiny individual effects rather than a few with large effects and why such an architecture makes it difficult to find robust associations between traits and genes. METHODS We conducted a genome-wide association study at 2 sites, Harvard University a...