BACKGROUND If height is a well-established risk factor for breast cancer, leg length and sitting height are usually considered as better candidate biomarkers of growth hormone exposure than height, respectively, in pre- and postpuberty. METHODS Risk of breast cancer associated with quartiles of height, sitting height, and leg length were estimated in the French E3N cohort (N = 50,704, includi...

Background: Prostate specific antigen (PSA) is an important biomarker to monitor patients after treated with radiation therapy (RT). The aim of this study is to evaluate the relationship between the PSA data and prostate cancer recurrence using the joint modeling. Methods: This historical cohort study was performed on 422 prostate cancer patients. Inclusion criteria included: patients with loc...

Background and objectives: There is a growing trend towards investigating natural products as sources of compounds with biological effects and many researches have been carried out in order to find effective medications against many diseases. Cancer is no exception and studies focusing on evaluating the effects of different materials on DNA, give valuable information in cancer researches and ca...

Male breast cancer is a rare disease with an increasing trend. Due to limited information especially about the genetic basis of the disease in Iran and the lower age of its onset, the disease requires more attention. The aim of this study was to screen the male patients with breast cancer for BRCA mutations as well as tissue markers of estrogen receptor (ER), progesterone receptor (PR), human e...

BACKGROUND Breast cancer is still considered as one of the most common female cancers worldwide regardless of the countries’ level of development. This study determines the incidence of breast cancer in Fars Province, Southern Iran. METHODS This study used patients' records from Shiraz University of Medical Sciences Cancer Registry Centre, which is a Hospital-Based Registry of Nemazee Hospit...

BACKGROUND Long-term physical activity may affect breast cancer risk. Few prospective studies have evaluated in situ or invasive breast cancer risk, or breast cancer receptor subtypes, in relation to long-term activity. METHODS We examined the association between recreational physical activity and risk of invasive and in situ breast cancer in the California Teachers Study, a cohort of women e...

PURPOSE To investigate the distribution of liver cancer mortality as well as its developing trend from l991 to 2012, forecast the future five-year trend, and provide a basis for the comprehensive prevention and management. MATERIALS AND METHODS Mortality data for liver cancer in China from 1991 to 2012 were used to describe characteristics and distribution of liver cancer mortality. Trend sur...

Background: Head and neck cancer is the sixth most common cancer in the world, with 690,000 new cases identified in 2012. There are some arguments over an increase or a decrease in the incidence rate of head and neck cancers in different locations. This study is conducted aimed at determining the frequency of head and neck cancers in patients referring to Rafsanjan Ali-ibn Abi Talib hospital pa...