Background and Objective: Oxidative stress induced by proinflammatory cytokines such as IL-1β plays a major role in β-cell destruction in diabetes type 1. Salvianolic acid B (Sal B) is a polyphenolic compound with antioxidant and protective effects. Thus, objective of this study was to assess the protection exerted by Sal B on isolated rat islets exposed to IL-1β and to investigate an underlyin...

objective: diabetes is a common endocrine disorder caused by deficiency of insulin secretion or insulin resistant. nowadays, in addition to trying to find a safe way to control diabetes, find the low side effect way is important. this study was designed to find the effect of urtica dioica extract on glycemic control and insulin resistance in patients with type 2 diabetes. materials and methods:...

In this paper we introduce a new scheme of censoring and study it under the Weibull distribution. This scheme is a mixture of progressive Type II censoring and self relocating design which was first introduced by Srivastava [8]. We show the superiority of this censoring scheme (PSRD) relative to the classical schemes with respect to “asymptotic variance”. Comparisons are also made with respect ...

Innate immune inflammatory responses are subject to complex layers of negative regulation at intestinal mucosal surfaces. Although the type I IFN system is critical for amplifying antiviral immunity, it has been shown to play a homeostatic role in some models of autoimmune inflammation. Type I IFN is triggered in the gut by select bacterial pathogens, but whether and how the type I IFN might re...

Our aim in this paper is to introduce some idea about generalized relative Nevanlinna order (α,β) and type of an analytic function with respect another the unit disc where α β are continuous non-negative functions on (-∞,+∞). So we discuss growth properties relating composition two basis as compared their corresponding left right factors.

Let Pn,r(x) be the generalized weighted power means. We consider bounds for the differences of means in the following form: max { Cu,v,β x 1 , Cu,v,β x n } σn,w′,β ≥ P n,u − P n,v α ≥ min { Cu,v,β x 1 , Cu,v,β x n } σn,w,β . Here β 6= 0, σn,t,β( x) = ∑n i=1 ωi[x β i −P β n,t(x)] andCu,v,β = u−v 2β2 . Some similar inequalities are also considered. The results are applied to inequalities of Ky Fa...

Increasing evidence has pointed to activated type I interferon signaling in tumors. However, the molecular basis for such activation and its role in tumorigenesis remain unclear. In the current studies, we report that activation of type I interferon (IFN) signaling in tumor cells is primarily due to elevated secretion of the type I interferon, IFN-β. Studies in oncogene-transformed cells sugges...

β-type titanium alloys with low Young's modulus are required to inhibit bone atrophy and enhance bone remodeling for implants used to substitute failed hard tissue. At the same time, these titanium alloys are required to have high static and dynamic strength. On the other hand, metallic biomaterials with variable Young's modulus are required to satisfy the needs of both patients and surgeons, n...