Microscopic polyangiitis is a small vessel vasculitis, associated with myeloperoxidaseantineutrophil cytoplasmic antibody. It rarely occurs in children. Central nervous system involvement in pediatric microscopic polyangiitis is not a well known entity with perhaps only five cases till date. We hereby present a 14-year-old girl with arthralgia, seizure, leukocytoclastic vasculitis, interstit...

BACKGROUND Atherosclerosis is the commonest cause of vascular disease which can involve peripheral and/or cardiac vessels. This study was conducted to evaluate the possible link between Ankle-Brachial Index (ABI) and coronary vessel involvement in patients with stable angina. METHODS This cross-sectional study was conducted in 2008 on 120 individuals who were hospitalized in Chamran Heart Cen...

this article engages with debates about the conceptualisation and practical challenges of patient and public involvement (ppi) in health and social care services. policy in this area in england has shifted numerous times but increasingly a consumerist discourse seems to override more democratic ideas concerning the relationship between citizens and public services. recent policy change in engla...

introduction: the wilson disease is an autosomal recessive disease in which the liver, central nervous system, eyes, blood and other parts of the body involved. timely diagnosis and appropriate treatment of the disease requires awareness of the clinical presentations of this disease in children.methods: this case series study included 62 patients with wilson disease who admitted to children&apo...

Magnetic resonance imaging (MRI) is very sensitive for the detection of white matter lesions (WML), which occur even in normal ageing. Intrinsic WML should be separated from physiological changes in the ageing brain, such as periventricular caps and bands, and from dilated Virchow-Robin spaces. Genuine WML are best seen with T2-weighted sequences such as long TR dual-echo spin-echo or FLAIR (fl...

Neurosarcoidosis is a rare manifestation of sarcoidosis, comprising 5-15% cases. We present case 44-year-old man with no prior medical history who experienced two episodes diffuse tonic-clonic seizures. Imaging showed dural-based lesion evidence brain parenchymal involvement, suggestive an aggressive, atypical meningioma invasion. He underwent resection and recovered well; histopathological ass...

background: stenting is currently the standard of care in percutaneous coronary intervention (pci). whether young patients remain at increased risk after pci in the present stent era has not been investigated widely. we evaluated angiographic characteristics and short- and mid-term outcomes in patients younger than 40 years of age who underwent pci. methods: from april 2003 to march 2005, prosp...