BACKGROUND Besides hypertension, obesity and the metabolic syndrome have recently emerged as risk factors for atrial fibrillation. This study sought to delineate the development of an arrhythmogenic substrate for atrial fibrillation in hypertension with and without concomitant obesity and metabolic syndrome. METHODS AND RESULTS We compared obese spontaneously hypertensive rats (SHR-obese, n=7...

Obesity results in abnormally high levels of triglyceride (TG) storage in tissues such as liver, heart, and muscle, which disrupts their normal functions. Recently, we found that lean mice challenged with high levels of dietary fat store TGs in cytoplasmic lipid droplets in the absorptive cells of the intestine, enterocytes, and that this storage increases and then decreases over time after an ...

We study the problem of (eeciently) deleting such clauses from conjunctive normal forms (clause-sets) which can not contribute to any proof of unsatissability. For that purpose we introduce the notion of an autarky system, associated with a canonical normal form for every clause-set by deleting superruous clauses. Clause-sets where no clauses can be deleted are called lean, a natural generaliza...

The purpose was to determine if glutamine supplementation would prevent a loss of lean mass in athletes during a 12-day weight reduction program. It was hypothesized that supplementation would spare lean body mass. Subjects (n=18) exercised and dieted to create a 4186kJ·day(-1) energy deficit and a 8372 kJ·day(-1) energy deficit on days 1-5, days 6-12, respectively. The glutamine (GLN) group (n...

While there are separate streams of established research on lean production, agile organization, and sustainable supply chain, the idea is to address the intersection of these three strategic initiatives in order to find synergies and competitive advantage for companies. The goal of the mission is to explore the link between supply chain and sustainable development with the insights of two main...

OBJECTIVE Lean mass is an important determinant of bone mineral density (BMD) accrual, yet data regarding its correlates based on multiethnic premenopausal women are lacking. We examined the influence of age, race/ethnicity, and lifestyle variables on total and regional lean mass distribution in this population. DESIGN A cross-sectional study was conducted on 708 healthy Black, White, and His...

The paper is a research-in-progress that focuses on examining the applicability of lean principles to the crowdsourcing process. While crowdsourcing is seen as an excellent exemplar of open innovation, there is no research that has focused on the wasteful, time-consuming or bloated nature of many crowdsourcing initiatives. This paper attempts to address this gap and examine the applicability of...

Nutritional status was studied in lung transplant (LT) candidates. The hypotheses were that nutritional depletion was highly prevalent and lean body mass depletion was a risk factor for a higher mortality both before and after LT. Of 78 consecutive patients listed for LT, 16 (21%) died while on the waiting list, eight (10%) were alive awaiting LT, and 54 (69%) received a graft. Mean age was 42....

Lean manufacturing is a business philosophy concerned with continually eliminating waste from processes while producing quality products greater efficiency. In addition to profits, organizations worldwide are beginning focus on environmental, social, and corporate-governance (ESG) factors because of the changing global environment. The Environmental Protection Agency has specifically stated tha...