Cranial neural crest (CNC) cells are a transient population of stem cells that originate at the border of the neural plate and the epidermis, and migrate ventrally to contribute to most of the facial structures including bones, cartilage, muscles and ganglia. ADAM13 is a cell surface metalloprotease that is essential for CNC cell migration. Here, we show in Xenopus laevis embryos that the Wnt r...

The problem of complex network clustering has been long studied and a satisfactory solution is still lack so far. By cohesion superiority of Gene Expression Programming and the information-theoretic topology compression framework, a novel algorithm, CNC-GEP, is proposed for complex network clustering. With no prior knowledge of the number of modules in networks, CNC-GEP not only determines the ...

This paper discussed about proposes an architecture and implementation of a controller via Function Block Development Kit (FBDK). It can be used to create an open CNC architecture on ISO 14649 and Function Block (IEC 61499). This offers interoperability, portability, and adaptability. The system framework consists of three main components: (1) STEP-NC Parser, (2) Tool Path Simulator, and (3) Co...

A parametric CNC (Computer Numerical Control) program was developed to make a test complex surface on a vertical milling machine equipped with an external fourth rotational axis. Parametric programming was used in order to get higher flexibility of the manufacturing process. The ball-end milling process was simulated and verified in a virtual model of the machine tool developed with the module ...

Computer hardware has become parallel in order to run faster and more efficient. One of the current standard parallel coding libraries is MPI (Message Passing Interface). The Intel Corporation is developing a new parallel software and translator called CnC (Concurrent Collections) to make programming in parallel easier. When using MPI, the user has to explicitly send and receive messages to and...

Abstract Nowadays, NURBS (Non-Uniform Rational B-Spline) method is widely used in CAD/CAM (Computer-Aided Design/Computer-Aided Manufacturing) to represent sculptured curves or surfaces. In this paper, we develop a 5-axis NURBS real-time interpolator and realize it in our developing CNC(Computer Numerical Control) system. At first, we use two NURBS curves to represent tool-tip and tool-axis pat...

In an ideal scenario of intelligent machine tools [18] the human mechanist was almost replaced by the controller. During the last decade many efforts have been made to get closer to this ideal scenario, but the way of information processing within the CNC did not change too much. The paper summarises the requirements of an intelligent CNC evaluating the different research efforts done in this f...