Fullerene C60 films deposited by sublimation were irradiated with Kr-F laser in a wide fluence interval from 15 to 40 mJ/cm2. In situ photoacoustic analysis was applied to study the phase transformation during the irradiation. The results obtained were discussed in conjunction with atomic force microscopy (AFM) and Raman spectroscopy data. It was found that for a irradiation fluence interval fr...

Background—Hypothermia is cardioprotective, but it causes Ca loading and reduced function on rewarming. The aim was to associate changes in cytosolic Ca with function in intact hearts before, during, and after cold storage with or without cardioplegia (CP). Methods and Results—Guinea pig hearts were initially perfused at 37°C with Krebs-Ringer’s (KR) solution (in mmol/L: Ca 2.5, K 5, Mg 2.4). O...

KCNH2 (hERG1) encodes the alpha-subunit proteins for the rapidly activating delayed rectifier K+ current (I(Kr)), a major K+ current for cardiac myocyte repolarization. In isolated myocytes I(Kr) frequently is small in amplitude or absent, yet KCNH2 channels and I(Kr) are targets for drug block or mutations to cause long QT syndrome. We hypothesized that KCNH2 channels and I(Kr) are uniquely se...

Juvenile hormone (JH) represses precocious metamorphosis of larval to pupal and adult transitions in holometabolous insects. The early JH-inducible gene Krüppel homolog 1 (Kr-h1) plays a key role in the repression of metamorphosis as a mediator of JH action. Previous studies demonstrated that Kr-h1 inhibits precocious larval-pupal transition in immature larva via direct transcriptional repressi...

Knowledge Representation & Reasoning (KR&R) is a fundamental topic in Artificial Intelligence. A basic KR language is First– Order Logic (FOL), the most representative logic–based representation language, which is part of almost any introductory AI course. In this work we present KRRT (Knowledge Representation & Reasoning Tutor). KRRT is a Web–based system which main goal is to help the student...

The pH profiles of the apparent biomolecular rate constants for the reaction f free EO with [2-'H]and [22H]phenylalanine (evaluated as (kr)H and (kr)H*, respectively, from rapid kinetic measurements and as the equivalent steady state coefficients ( & l ) ~ and (+I-')"*) show that k , = k', k2 >> k-' << k2* and that the ionization controlled by K', (= kL,/k,) is at virtual equilibrium. The expre...

We present a family of identities ‘cyclic sum formula’ and ‘sum formula’ for a version of multiple q-zeta star values. We also discuss a problem of q-generalization of shuffle products. Introduction and notation The classical idea of introducing an additional parameter to an expression or formula we wish to deal with, is quite fruitful in many situations. This may simplify a proof of the corres...

BACKGROUND Hypothermia is cardioprotective, but it causes Ca(2+) loading and reduced function on rewarming. The aim was to associate changes in cytosolic Ca(2+) with function in intact hearts before, during, and after cold storage with or without cardioplegia (CP). METHODS AND RESULTS Guinea pig hearts were initially perfused at 37 degrees C with Krebs-Ringer's (KR) solution (in mmol/L: Ca(2+...

Insect larvae metamorphose to winged and reproductive adults either directly (hemimetaboly) or through an intermediary pupal stage (holometaboly). In either case juvenile hormone (JH) prevents metamorphosis until a larva has attained an appropriate phase of development. In holometabolous insects, JH acts through its putative receptor Methoprene-tolerant (Met) to regulate Krüppel-homolog 1 (Kr-h...