نتایج جستجو برای: مد tem

تعداد نتایج: 47549  

Journal: :Microscopy and Microanalysis 2010

2014
A. Delobbe O. Salord T. Hrncir A. David P. Sudraud F. Lopour

Preparation of Transmission Electron Microscope (TEM) samples by Focused Ion Beam (FIB) milling is one of the most precise techniques now routinely used for example in failure analysis or material science. These TEM samples are commonly prepared using Ga FIB technology, starting more than 20 years ago [13]. Presently FIB columns are commonly combined with the Scanning Electron Microscopy (SEM) ...

ژورنال: مدیریت فرهنگی 2008
ابوذر فردی بیرانوند علی رشید پور مهدی ماسوری

مقاله حاضر که پژوهشی در حوزه ی مد و فرهنگ می باشد، در ابتدا با تعریفی جامع از مد و فرهنگ و نقش وتاثیر آن در جامعه، به بررسی ماهیت مد و انواع آن در جوام ع مختلف می پردازد. با گذری بر نحوه پیدایش مد و مدگرایی در جوامع مختلف و نحوه زوال آنها، به ضرورت و اهمیت مدیریت مد در سطح جوامع اشاره می کند و در ادامهضمن بحث در مورد مراحل مدیریت پدیده ی م د، به ارائه الگوی مدیریتی آن می پردازد. در پایان به این...

2017
Kei Kawaguchi Kentaro Igarashi Shukuan Li Qinghong Han Yuying Tan Tasuku Kiyuna Kentaro Miyake Takashi Murakami Bartosz Chmielowski Scott D. Nelson Tara A. Russell Sarah M. Dry Yunfeng Li Michiaki Unno Fritz C. Eilber Robert M. Hoffman

An excessive requirement for methionine termed methionine dependence, appears to be a general metabolic defect in cancer. We have previously shown that cancer-cell growth can be selectively arrested by methionine deprivation such as with recombinant methioninase (rMETase). The present study used a previously-established patient-derived orthotopic xenograft (PDOX) nude mouse model of BRAF V600E-...

2016
Kei Kawaguchi Kentaro Igarashi Takashi Murakami Bartosz Chmielowski Tasuku Kiyuna Ming Zhao Yong Zhang Arun Singh Michiaki Unno Scott D. Nelson Tara A. Russell Sarah M. Dry Yunfeng Li Fritz C. Eilber Robert M. Hoffman

Melanoma is a recalcitrant disease in need of transformative therapuetics. The present study used a patient-derived orthotopic xenograft (PDOX) nude-mouse model of melanoma with a BRAF-V600E mutation to determine the efficacy of temozolomide (TEM) combined with tumor-targeting Salmonella typhimurium A1-R. A melanoma obtained from the right chest wall of a patient was grown orthotopically in the...

2017
Huae Xu Feng Jia Pankaj Kumar Singh Shu Ruan Hao Zhang Xiaolin Li

The anti-glioma effect of temozolomide (Tem) is sometimes undermined by the emerging resistance. Recently, resveratrol (Res), herbal medicine extracted from grape seeds, has been demonstrated for its potential use in chemosensitization. In the current study, both these drugs were loaded simultaneously into nanoparticles with methoxy poly(ethylene glycol)-poly epsilon caprolactone (mPEG-PCL) as ...

Journal: :American journal of physiology. Cell physiology 2012
Pilar Alcaide Roberta Martinelli Gail Newton Marcie R Williams Alejandro Adam Peter A Vincent Francis W Luscinskas

Leukocyte transendothelial migration (TEM) is regulated by several signaling pathways including Src family kinases (SFK) and the small RhoGTPases. Previous studies have shown that vascular endothelial-cadherin (VE-cad) forms a complex with β-,γ-, and p120-catenins and this complex disassociates to form a transient gap during leukocyte TEM. Additionally, p120-catenin (p120-1A) overexpression in ...

2014
C. Barry Carter

In this invited talk, I will suggest where we are in our use of TEM for imaging extended defects and guess where we are going. Since the topic of this Symposium concerns advances in imaging and quantification of strain, local atomic structure, and the chemistry of extended defects, the present talk will emphasize the history and development of diffraction contrast methods for the analysis of ex...

Journal: :Microscopy Today 2000

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