Aim:Spitz naevus is a benign melanocytic tumour with distinct histopathological features of spindle-shaped melanocytes. An understanding genetic aberrations can help to characterise the different subsets Spitzoid neoplasms. Anaplastic lymphoma kinase (ALK) tyrosine receptor that was first described in pathogenesis anaplastic large cell (ALCL). ALK mutations have been reported up 10% Spitz tumou...

BackgroundThe aim of this multicenter retrospective study was to compare early and midterm clinical hemodynamic results aortic valve replacement with rapid-deployment bioprostheses performed through conventional full-sternotomy vs mini-sternotomy.MethodsData from the Italian registry (INTU-ITA registry) were analyzed. Patients divided into 2 groups: full sternotomy (FS) ministernotomy (MS). Pri...