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Background/Aim: Vitiligo is a prevalent inflammatory illness that can affect the skin and mucosal surfaces characterized by patchy loss of pigmentation. Paraoxonase1 (PON1) an esterase enzyme with antioxidant properties binds to high-density lipoproteins. We examined whether PON1 gene Q192R polymorphism risk factor for vitiligo among Turkish people.
 Methods: The study included 70 controls...
Background and purpose: Colorectal cancer is one of the most common cancers in the world and Iran. This cancer is a multifactorial disease that is induced by interaction of various genetic and environmental factors. In this study, we investigated the interactions between different environmental factors and candidate polymorphisms of two genes in colorectal cancer X-ray repair cross-complementin...
The antigen content of plasminogen activator inhibitor-1 (PAI-1) in primary breast cancer tissue extracts may be of strong prognostic value: high levels of PAI-1 in tumors predict poor prognosis for patients. The gene encoding PAI-1 is highly polymorphic and an insertion (5G)/deletion (4G) polymorphism in the PAI-1 gene promoter (the 4G/5G polymorphism), may have functional significance in PAI-...
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