Mesenchymal stem cells (MSCs) are, due to their immunomodulatory characteristics, utilized in therapy of immune-mediated diseases. We used murine model of cisplatin nephrotoxicity to explore the effects of MSCs on immune cells involved in the pathogenesis of this disease. Intraperitoneal application of MSCs significantly attenuated cisplatin nephrotoxicity, decreased inflammatory cytokines TNF-...

This study is about the craniofacial indices and neuromorphometrics of the Nigerian local pig and has been performed on twelve males and fourteen females of ages one and a half to two years. The average values obtained for the tongue length, tongue weight, rasp length, left pinna length, right pinna length, left pinna width, right pinna width, height of left external nares, height of right exte...

BACKGROUND We summarize our experience of the diagnosis, surgical treatment, and prognosis of solid pseudopapillary tumors (SPTs). METHODS We carried out a retrospective study of clinical data from a series of 17 patients with SPT managed in two hospitals between October 2001 and November 2011. RESULTS All of the 17 patients were female and the average age at diagnosis was 26.6 years (range...

We measured the galactic hydrogen column densities to the neutron-star binaries GX 17+2, 4U 1705−44, and 4U 1728−34 by modeling the Mg and Si absorption edges found in high-resolution X-ray spectra obtained by the Chandra X-ray Observatory. We found for GX 17+2, NH = (2.38 ± 0.12) × 10 22 cm, for 4U 1705−44, NH = (2.44 ± 0.09) × 10 cm, and for 4U 1728−34, NH = (2.49 ± 0.14) × 10 22 cm. These va...

To identify genetic determinants of lipoprotein levels, we are performing quantitative trait locus (QTL) analysis on a series of mouse intercrosses in a "daisy chain" experimental design, to increase the power of detecting QTL and to identify common variants that should segregate in multiple intercrosses. In this study, we intercrossed strains CAST/Ei and 129S1/SvImJ, determined HDL, total, and...

Extensive limb lengthening (ELL) was completed in 75 patients: 66 achondroplasia and 9 hypochondroplasia. The average 27 cm for (12–40 cm) 17 hypochondroplasia (range 10–25 cm). There were 48 females males. Lengthening done either by 2-segment (14 patients; both tibias and/or femurs) or 4-segment lengthenings (64 femurs at the same time). Most patients also had bilateral humeral lengthening. Pa...

Ollier's disease is characterised by severe deformity of the extremities and retarded growth because of multiple enchondromas. For correction of deformity, the Ilizarov method has been used although it has many complications. A 17-year-old boy with Ollier's disease had a limb-length discrepancy of 17.4 cm, with a valgus deformity of the right knee and recurvatum of the femur of 23 degrees . He ...

The Bernoulli effect may result in eruption of a vulnerable carotid atheroma, causing a stroke. We measured electrocardiography (ECG)-registered QRS intra-stenotic blood velocity and atheroma strain dynamics in carotid artery walls using ultrasonic tissue Doppler methods, providing displacement and time resolutions of 0.1 μm and 3.7 ms. Of 22 arteries, 1 had a peak systolic velocity (PSV) >280 ...