نتایج جستجو برای: 2 ratio
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The binding of mithramycin A to d(ACCCGGGT)2 has been investigated by one- and two-dimensional 1H NMR spectroscopy. Titration of the drug into the octamer solution results in loss of the oligonucleotide C2 symmetry at stoichiometric ratios less than 4 drug molecules per duplex. However, at a ratio of 4:1 (drug/duplex), the C2 symmetry of the oligonucleotide is restored. From these data it is ev...
جهت ارزیابی کمی آثار بیماری های لوکوز گاوی، رینوتراکئیت عفونی گاوی، یون و نئواسپوروزیس بر عملکرد تولیدی، تولید مثلی و نرخ حذف در یک گله گاو شیری صنعتی مطالعه حاضر طراحی و اجرا شد. در زمان تست در گله 638 رأس گاو شیری حضور داشتند که نتیجه تست برای آن ها مشخص بود و وارد مطالعه شدند. برای هر گاو سن دام، شکم زایش، وضعیت زایمان (طبیعی، سخت زایی یا مرده زایی و سقط) و تاریخ زایش برای اولین زایمان پس از...
Background: Bax and Bcl-2 are the major members of Bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. Therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. Methods: In this study, the relative level of mRNA expression of Bax and Bcl-2 genes was deter...
BACKGROUND It has been postulated that non-steroidal anti-inflammatory drugs (NSAIDs) use leads to decreased prostate cancer (PCa) risk. In recent years, NSAIDs' role in PCa development has been extensively studied; however, there is not yet a definitive answer. Moreover, the epidemiological results for NSAIDs' effect on PCa-specific mortality have been inconsistent. Therefore, we performed a m...
BACKGROUND Observational studies and randomized trials have reported increased cardiovascular risk associated with cyclooxygenase-2 inhibitors. Prior placebo-controlled randomized studies had limited ability to assess the relationship of either celecoxib dose or pretreatment cardiovascular status to risk associated with celecoxib. Our aim was to assess the cardiovascular risk associated with ce...
The spatial and temporal dynamics of two intracellular second messengers, cAMP and Ca2 , were simultaneously monitored in living cells by digital fluorescence ratio imaging using FICRhR, a single-excitation dualemission cAMP indicator, and fura-2, a dual-excitation singleemission Ca2+ probe. In single C6-2B glioma cells, isoproterenolor forskolin-evoked cAMP accumulation (measured in vivo as an...
the ratio of cd4+/cd8+ has been used as a clinically index to evaluate patients' immunity. numerous researchers have studied cd4+/cd8+ ratio in pulmonary tuberculosis (ptb) patients. however, the change of cd4+/cd8+ ratio remains controversial. we present a meta-analysis of 15 case-control studies to identify the change of cd4+/cd8+ ratio in ptb patients.we assessed heterogeneity of effect esti...
simplification universal as a universal feature of translation means translated texts tend to use simpler language than original texts in the same language and it can be critically investigated through common concepts: type/token ratio, lexical density, and mean sentence length. although steps have been taken to test this hypothesis in various text types in different linguistic communities, in ...
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