SB-209247 [(E)-3-[6-[[(2,6-dichlorophenyl)-thio]methyl]-3-(2-phenylethoxy)-2-pyridinyl]-2-propenoic acid], an anti-inflammatory leukotriene B4 receptor antagonist, was associated in beagle dogs but not male rats with an inflammatory hepatopathy. It also produced a concentration-dependent (10-1000 microM) but equal leakage of enzymes from dog and rat precision-cut liver slices. The hepatic metab...

A Sarvate–Beam Triple System SB(v, 3) is a set V of v elements and a collection of 3–subsets of V such that each distinct pair of elements in V occurs in i blocks, for every i in the list 1, 2, . . . , ( v 2 ) . In this paper, we completely enumerate all Sarvate-Beam Triple Systems for v = 5 and v = 6. (In the case v = 5, we extend a previous result of R. Stanton [8].) 1 Sarvate–Beam Designs Th...

BACKGROUND Suicidal patients admitted to a psychiatric hospital are considered to be at risk of suicidal behavior (SB) and suicide. The present study aimed to seek predictors of SB recurrence of the high-risk patients by examining their post-hospitalization course. METHOD The design was 2-year prospective follow-up study of patients consecutively admitted with SB to a psychiatric center in To...

In this paper we show that the compactness of a Loeb space depends on its cardinality, the nonstandard universe it belongs to and the underlying model of set theory we live in. In §1 we prove that Loeb spaces are compact under various assumptions, and in §2 we prove that Loeb spaces are not compact under various other assumptions. The results in §1 and §2 give a quite complete answer to a quest...

BACKGROUND Coronary hemodynamics and physiology specific for bifurcation lesions was not well understood. To investigate the influence of the bifurcation angle on the intracoronary hemodynamics of side branch (SB) lesions computational fluid dynamics simulations were performed. METHODS A parametric model representing a left anterior descending-first diagonal coronary bifurcation lesion was cr...

The asymmetric unit of the title compound, (C(6)H(14)N)(2)[SbCl(5)], contains one cation and half of the anion on a special position (specifically, the Sb(III) ion and three chloride anions are situated on a mirror plane). In the [SbCl(5)](2-) unit, the Sb(III) ion is coordinated by five chloride anions [Sb-Cl = 2.3721 (11)-2.6656 (12) Å] in a distorted square-pyramidal geometry. However, one c...

The mechanism of the antidepressant-like activity of the selective 5-hydroxytryptamine(6) (5-HT(6) receptor antagonist N-[3,5-dichloro-2-(methoxy)phenyl]-4-(methoxy)-3-(1-piperazinyl)benzenesulfonamide (SB-399885) was studied in the forced swim test in rats. SB-399885 administered intraperitoneally at a single dose of 10 mg/kg potently shortened the immobility time in rats. That potential antid...

Positron annihilation measurements, supported by first-principles electron-structure calculations, identify vacancies and vacancy clusters decorated by 1-2 dopant impurities in highly Sb-doped Si. The concentration of vacancy defects increases with Sb doping and contributes significantly to the electrical compensation. Annealings at low temperatures of 400-500 K convert the defects to larger co...