Irosustat is a first-generation, irreversible, steroid sulfatase inhibitor currently in development for hormone-dependent cancer therapy. To predict clinical drug-drug interactions between irosustat and possible concomitantly administered medications, the inhibition/induction potential of irosustat with the main drug-metabolizing enzymes was investigated in vitro. The interaction of aromatase i...

background: resistin and ghrelin are hormones that have roles in the glucose and lipid homeostasis and weight regulation. human studies regarding resistin and ghrelin in diabetic patients are scarce, especially in the cases of normotensive and non-obese patients. this study was designed to illuminate some of the missing points.methods: eighty diabetic patients and eighty healthy individuals par...

Comparative lifetime tests are extremely significant when the experimenters study reliability of comparative advantages two products in competition. Considering joint type-II censoring, we deal with inference product lines conform to Gumbel distributions. The maximum likelihood estimations population parameters were obtained current research. An approximate confidence interval and a simultaneou...

The Journal of Asian Studies / Volume 74 / Issue 03 / August 2015, pp 667 686 DOI: 10.1017/S002191181500056X, Published online: 18 August 2015 Link to this article: http://journals.cambridge.org/abstract_S002191181500056X How to cite this article: Jisoo M. Kim (2015). Women's Legal Voice: Language, Power, and Gender Performativity in Late Chosŏn Korea. The Journal of Asian Studies, 74, pp 667-6...

age related cytochemical changes of thymic endocrine cells were studied in 78 day old chicks at five day interval to age of day 60 employing a panel of cytochemical stains. methenamine silver revealed cell morphology including cell processes distinctly while diamine silver revealed a stronger argentaffinity in these cells. the cells had greater affinity for diamine silver compared to methenamin...

This article presents the analysis of the Type-II hybrid progressively censored data when the lifetime distributions of the items follow Type-II generalized logistic distribution. Maximum likelihood estimators (MLEs) are investigated for estimating the location and scale parameters. It is observed that the MLEs can not be obtained in explicit forms. We provide the approximate maximum likelihood...

This paper considers parameter estimations in Lomax distribution under progressive type-II censoring with random removals, assuming that the number of units removed at each failure time has a binomial distribution. The maximum likelihood estimators (MLEs) are derived using the expectation-maximization (EM) algorithm. The Bayes estimates of the parameters are obtained using both the squared erro...