Hepatocyte-specific Phosphatase and tensin homolog (Pten)-knockout (KO) mice exhibit hepatic lesions analogous to non-alcoholic steatohepatitis (NASH). 1,8-cineole is a monoterpene oxide and it has several biological effects including hepatoprotective effects. In this study we revealed that 1,8-cineole ameliorates NASH of Pten KO mice. Pten KO mice were assigned to a control group without any m...

This study aimed to assess ecological quality status of hard substratum macroinvertebrates communities of the Caspian Sea with three ecological indices and their relation with environmental factors. For this purpose benthic communities of the Caspian Sea basin were studied seasonally during 2014 in 8 sampling sites. Temperature, salinity, dissolved oxygen, pH, nitrate, nitrite, silicate and pho...

Background & Aim: The Lamiaceae or Labiatae (commonly referred to as the mint or deadnettle family) are an exceedingly large and widespread of flowering plants (Angiospermae). Most member of Lamiaceae plants are used in Iranian folk medicine as stimulant, antiseptic, aphrodisiac, stomachic, expectorant, carminative, anti-diarrheic and anti-bacterial. The aim of the present work was to obtain a ...

the effect of environmental factors on plant vegetation is different. therefore, it is necessary to evaluate role of these factors in medicinal plants growth, development and essential oil. this study was performed to investigate the effect of factors on qualitative and quantitative variations of the essential oil of verbascum songaricum in its habitats in central zagros mountains, iran in 2012...

The in vivo metabolic fate of 1,8-cineole was investigated in six male koalas. Koalas were fed ad lib a diet of Eucalyptus cephalocarpa leaf with a 1,8-cineole concentration of 2.53+/-0.70% dry mass of leaf, corresponding to a 1,8-cineole intake of 2.4+/-1.1 mmol/kg (3.1+/-1.3 g). Urine and faeces were collected for 24 h and metabolites identified by GC-MS and LC-MS. Metabolites were quantified...

the achillea l. genus has a wide distributional range, and the differences in oil composition may be affected by different environmental factors such as soil mineral fertilization, the climate conditions and the culture site. to evaluate the effect of temperate climate on content and chemical combination of essential oil of achillea filipendulina lam,  a. arabica kotschy and a. eriophora dc., t...

Introduction: This study was conducted to evaluate the influence of chitosan Nano-gel/emulsion coating functionalized by Ziziphora clinopodioides essential oil (ZCEO) and nisin on growth inhibition of Escherichia coli O157: H7 inoculated in beef samples during 16 days in cold storage condition (4˚C). Methods: Beef sample ...

We investigated the effect of cineole on the expression of genes related to reverse cholesterol transport and hepatic fatty acid metabolism. Cineole, a small aroma compound in teas and herbs, significantly stimulated the transactivation of liver X receptor modulator (LXR)-α and LXR-β. The mRNA and protein expression of LXRs and their target genes, including ABCA1 and ABCG1, was significantly in...