introduction in order to treat uveal melanoma , first, radioactive seeds are laid on a silicone- made substance which is called silastic after that they are inserted in the plaque, and finally, this plaque containing silicone-made substance is stitched to the sclera surface. the dose gradient within the tumor and healthy tissues can be varied due to changing the silastic thickness between scler...

Background: The increasing amount of sewage sludge (SS) and more legislative regulation of its disposal have stimulated the need for developing new technologies including gamma irradiation to recycle SS efficiently. Objective: To evaluate the effects of gamma irradiated and non-irradiated SS (SSGI and SSNI, respectively) on essential oil (EO) content and composition of Ocimum basilicum L. Me...

Introduction: Breast cancer is the most common cancer among women. Brachytherapy is one of the ways to treat breast cancer. In brachytherapy treatments, high-dose sources are used in interstitial placement. Here, Iridium-192 is used. This source emits gamma rays with energies ranging from 136 kV to 1060 kV electron volts. The activity of the used spring is 10 Ci. The simulated ...

BACKGROUND Somatostatin analogue-based radionuclide therapy with (177)Lu-DOTATATE is an important treatment option for patients with advanced neuroendocrine tumours overexpressing somatostatin receptors. In addition to the kidneys, the bone marrow is a major dose-limiting organ. The correlation between developed haematological toxicity and absorbed dose to the bone marrow is poor, which indicat...

Peptide receptor radionuclide therapy (PRRT) is an effective MRT (molecular radiotherapy) treatment, which consists of multiple administrations of a radiopharmaceutical labelled with 177Lu or 90Y. Through sequential functional imaging a patient specific 3D dosimetry can be derived. Multiple scans should be previously co-registered to allow accurate absorbed dose calculations. The purpose of thi...

Introduction: Development of a novel radiopharmaceutical needs assessment of its biological- distribution in animal models, most commonly mice prior to its common application. This study describes the biodistribution and absorbed dose prediction 131I-MIBG in human organs after injection in mice.   Materials and Methods: In this research, 131I-MIBG radiopha...

Introduction Proton therapy is used to treat malignant tumors such as melanoma inside the eye. Proton particles are adjusted according to various parameters such as tumor size and position and patient’s distance from the proton source. The purpose of this study was to assess absorbed doses in eyes and various tumors found in the area of sclera and choroid and the adjacent tissues in radiotherap...