Lipomembranous panniculitis is a special type of fat necrosis which has been associated with several clinical conditions, mainly chronic venous insufficiency and connective tissue disorders such as lupus profundus, morphea, systemic sclerosis, and dermatomyositis .We report a 50 yearold woman with known rheumatoid arthritis who presented with a painful indurated erythematous plaque on her right...

purpose: to report bilateral terrien’s marginal degeneration, circumferential peripheral corneal ectasia and posterior polymorphous dystrophy in a patient with rheumatoid arthritis. case report: a 24-year-old male patient, who was known case of rheumatoid arthritis from 8 years before, presented with decreased vision since four years ago. comprehensive ophthalmic eye exami-nation revealed bilat...

rheumatoid arthritis is a chronic inflammatory disease characterized by the sequestration of various leukocyte subpopulations within both the developing pannus and synovial space. this study was undertaken to examine the therapeutic potency of tindurin in experimental rheumatoid arthritis. collagen-induced arthritis (cia) was induced by intradermally immunization of lewis rats at the base of th...

OBJECTIVE To evaluate the clinical efficacy, safety, and tolerability of clarithromycin in patients with rheumatoid arthritis. RESEARCH DESIGN AND METHODS This was a 6-month, monocenter, randomized, double-blind, placebo-controlled study. A total of 81 patients with early rheumatoid arthritis were treated with either once-daily oral clarithromycin (500 mg) or daily oral placebo for 6 months. ...

The rheumatoid factor, a group of unusual macroglobulins, is demonstrable in the serum of the majori ty of patients with rheumatoid arthritis and in a relatively small proportion of patients with other diseases (1). The presence of this factor can be demonstrated by its reaction with human v-globulin (Cohn fraction I I ) in such serological procedures as the tanned sheep cell agglutination (2) ...

Cytokines play key roles in spontaneous CD4(+) T cell-mediated chronic autoimmune arthritis in SKG mice, a new model of rheumatoid arthritis. Genetic deficiency in IL-6 completely suppressed the development of arthritis in SKG mice, irrespective of the persistence of circulating rheumatoid factor. Either IL-1 or TNF-alpha deficiency retarded the onset of arthritis and substantially reduced its ...

Penicillamine has been used in the treatment of patients with rheumatoid arthritis with variable clinical response (Jaffe, 1963; Camus, Guillien, Crouzet, Schaeffer, and Lievre, 1970; Zuckner, Ramsey, Dorner, and Gantner, 1970; Golding, Wilson, and Day, 1970). Moreover, observations on the effect of this drug on serum immunoglobulins and rheumatoid factor titres have yielded conflicting and ind...

objective(s) recent studies on human indicate that the introduction of therapeutic use of tolerogenic dendritic cell (dc) for chronic inflammatory conditions is imminent. for the purpose of defining cgrp potency in tolerogenic dc production, we investigated the phenotype and il-'2 production of dcs generated from the monocytes of rheumatoid arthritis (ra) patients in the presence of the ca...

introduction: rheumatoid arthritis (ra) is the most common autoimmune joint disease. osteoporosis is a well-known consequence of ra. objective: the aim of the present study was to determine the interrelationship between radiographic findings and bone mineral density (bmd) in patients with ra. methods: 70 patients with established ra (according to 1987 acr criteria) were included in a cross-sect...

background: this study aims to investigate the effect of antioxidants supplement on clinical outcomes and antioxidant parameters in rheumatoid arthritis (ra). methods: the pre‑post study was conducted on 40 female patients with ra in 12 weeks that taken daily one “selenplus” capsule contained 50 μg selenium, 8 mg zinc, 400 μg vitamin a, 125 mg vitamin c, and 40 mg vitamin e. about 5 ml venous b...